Background: Working memory (WM) abilities are frequently impaired in neurological disorders affecting fronto-parietal cortical/sub-cortical structures. WM deficits negatively influence interventional outcomes and everyday functioning. This study thus aimed at the following: (a) developing and standardizing an ecologically valid task for WM assessment ( Ice Cream Test, ICT); (b) validating and norming a novel WM test (Digit Ordering Test, DOT), as well as providing updated norms for digit span (DS) tasks, in an Italian population sample; (c) introducing a novel scoring procedure for measuring WM.
Methods: One-hundred and sixty-eight Italian healthy participants-73 male, 95 females; age: 48.4 ± 19.1 (18-86); education: 12.1 ± 4.8 (4-21)-underwent a thorough WM assessment-DOT, ICT, and both forward and backward DS tasks (FDS, BDS). The ICT requires participants to act as waiters who have to keep track of customers' orders. For each task, WM and total (T) outcomes were computed, i.e., the number of elements in the longest sequence and that of recalled sequences, respectively. Norms were derived via the equivalent score (ES) method.
Results: DS ratios (DSRs) were computed for both WM/S and T outcomes on raw DS measures (BDS divided by FDS). Age and education significantly predicted all WM tasks; sex affected FDS and DSR-T scores (males > females). WM measures were highly internally related.
Discussion: The present work provides Italian practitioners with a normatively updated, multi-component, adaptive battery for WM assessment (WoMAB) as well as with novel outcomes which capture different WM facets-WM capacity and attentive monitoring abilities.
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http://dx.doi.org/10.1007/s10072-021-05416-7 | DOI Listing |
Adv Sci (Weinh)
December 2024
Department of Mechanical Engineering, University of Washington, Seattle, WA, 98195, USA.
Vitrimer is a new, exciting class of sustainable polymers with healing abilities due to their dynamic covalent adaptive networks. However, a limited choice of constituent molecules restricts their property space and potential applications. To overcome this challenge, an innovative approach coupling molecular dynamics (MD) simulations and a novel graph variational autoencoder (VAE) model for inverse design of vitrimer chemistries with desired glass transition temperature (T) is presented.
View Article and Find Full Text PDFJ Clin Med
December 2024
Department of Exercise Sciences, University of Auckland, Auckland 1010, New Zealand.
Cardiac rehabilitation, a multi-component intervention designed to mitigate the impact of cardiovascular disease, often underutilises low-intensity resistance exercise despite its potential benefits. This narrative review critically examines the mechanistic and clinical evidence supporting the incorporation of low-intensity resistance exercise into cardiac rehabilitation programmes. Research indicates that low-intensity resistance exercise induces hypertrophic adaptations by maximising muscle fibre activation through the size principle, effectively recruiting larger motor units as it approaches maximal effort.
View Article and Find Full Text PDFJ Cancer Educ
December 2024
University of New Mexico Comprehensive Cancer Center, University of New Mexico Health Sciences Center, Albuquerque, NM, USA.
American Indians (AIs) experience continued disparities in incidence, mortality, and survival on cancers responsive to early screening in the USA. In New Mexico, AIs compared with other racial/ethnic populations are substantially less likely to adhere to recommended screening guidelines. Our study focuses on increasing cancer awareness using culturally, linguistically, and health literacy appropriate informational materials.
View Article and Find Full Text PDFPhys Ther
December 2024
School of Rehabilitation, Medicine Faculty, Université de Montréal, Montréal, Québec, Canada.
Objective: Suboptimal primary health care management of shoulder pain has been reported in previous studies. Implementing clinical practice guidelines (CPGs) recommendations using a theoretical approach is recommended to improve shoulder pain management. This study aims to identify determinants for implementing recommendations from shoulder CPGs to help develop an intervention based on the identified determinants.
View Article and Find Full Text PDFSci Rep
December 2024
Department of Maritime and Transport Technology, Faculty of Mechanical Engineering, Delft University of Technology, Delft, 2628CD, The Netherlands.
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