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Diagnosing dementia in the Arctic: translating tools and developing and validating an algorithm for assessment of impaired cognitive function in Greenland Inuit. | LitMetric

AI Article Synopsis

  • The study focuses on improving cognitive function assessments for aging populations in Arctic Greenland by translating and evaluating relevant tools.
  • An expert panel selected the Mini-Cog and RUDAS as suitable tools, which were then translated and validated through a rigorous process across three medical locations.
  • Testing revealed that the Mini-Cog and RUDAS scores were significantly associated, with differing sensitivities and specificities, leading to recommendations for referrals based on specific score thresholds for further evaluation.

Article Abstract

The ageing Arctic populations raise the need for work-up of cognitive function that reflects language and cultural understandings. To translate and evaluate tools for work-up of cognitive impairment in Greenland. Step A: An expert panel was established to select tools suitable for the work-up of cognitive impairment at three different settings in Greenland. Step B: Tools were translated in a multiple-step process of independent translations with back-translation and adaptations by two independent translators and two Greenlandic physicians. Step C: a testing and validation process of the tools at three locations: the national hospital in the capital city; regional hospital in a town; health care centre in a small town. Tools selected were Mini-Cog and RUDAS. Participants for testing of tools were 43 of 61 invited, of which six had dementia. RUDAS and Mini-Cog scores were associated (p < 0.001). The smoothed AUC was 0.87 (95%-CI, 0.65-0.95) for Mini-Cog and 0.90 (95%-CI, 0.76-0.97) for RUDAS. The sensitivity of Mini-Cog with a cut-off at ≤3 was 83.3%, and specificity was 62.2%. For RUDAS with a cut-off at ≤23, these were 100% and 75.7%, respectively. Requested tools have been translated for assessing cognitive function in the native Arctic setting. Small town residents with a Mini-Cog score of 3 or lower should be referred to a regional hospital for RUDAS, and a score of 23 or less should cause referral to the national hospital for a full work-up of cognitive function.

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Source
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC8245097PMC
http://dx.doi.org/10.1080/22423982.2021.1948247DOI Listing

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