AI Article Synopsis
- The text highlights significant discoveries related to the CREB protein's role in memory consolidation, showcasing the success of Molecular and Cellular Cognition (MCC) in neuroscience.
- It contrasts two philosophical approaches— "mechanism" and "ruthless reductionism"—which interpret these findings differently, with the author advocating for the latter as a more fitting explanation for the experimental designs and discussions.
- Finally, it prompts a broader philosophical dialogue on how cellular and molecular insights connect with larger systems in neuroscience.
Article Abstract
I recount some landmark discoveries that initially confirmed the cyclic AMP response element-binding (CREB) protein-memory consolidation and allocation linkages. This work constitutes one of the successes of the field of Molecular and Cellular Cognition (MCC) but is also of interest to philosophers of neuroscience. Two approaches, "mechanism" and "ruthless reductionism", claim to account for this case, yet these accounts differ in one crucial way. I explain this difference and argue that both the experiment designs and discussions of these discoveries by MCC scientists better fit the ruthless reductionist's account. This conclusion leads to further philosophical discussion about how discoveries in cellular/molecular neurobiology integrate with systems neuroscience findings.
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|---|---|
| http://www.ncbi.nlm.nih.gov/pmc/articles/PMC8222766 | PMC |
| http://dx.doi.org/10.3934/Neuroscience.2021017 | DOI Listing |
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The first two decades of CREB-memory research: data for philosophy of neuroscience.
AIMS Neurosci
February 2021
Department of Philosophy, Mississippi State University; Department of Neurobiology and Anatomical Sciences, University of Mississippi Medical Center. USA.
Article Synopsis
- The text highlights significant discoveries related to the CREB protein's role in memory consolidation, showcasing the success of Molecular and Cellular Cognition (MCC) in neuroscience.
- It contrasts two philosophical approaches— "mechanism" and "ruthless reductionism"—which interpret these findings differently, with the author advocating for the latter as a more fitting explanation for the experimental designs and discussions.
- Finally, it prompts a broader philosophical dialogue on how cellular and molecular insights connect with larger systems in neuroscience.
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