A fundamental issue of network data science is the ability to discern observed features that can be expected at random from those beyond such expectations. Configuration models play a crucial role there, allowing us to compare observations against degree-corrected null-models. Nonetheless, existing formulations have limited large-scale data analysis applications either because they require expensive Monte-Carlo simulations or lack the required flexibility to model real-world systems. With the generalized hypergeometric ensemble, we address both problems. To achieve this, we map the configuration model to an urn problem, where edges are represented as balls in an appropriately constructed urn. Doing so, we obtain the generalized hypergeometric ensemble of random graphs: a random graph model reproducing and extending the properties of standard configuration models, with the critical advantage of a closed-form probability distribution.
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http://dx.doi.org/10.1038/s41598-021-92519-y | DOI Listing |
Sci Rep
December 2024
BAOBAB Unit, NeuroSpin center, CEA, Université Paris-Saclay, Gif-sur-Yvette, France.
Decoding states of consciousness from brain activity is a central challenge in neuroscience. Dynamic functional connectivity (dFC) allows the study of short-term temporal changes in functional connectivity (FC) between distributed brain areas. By clustering dFC matrices from resting-state fMRI, we previously described "brain patterns" that underlie different functional configurations of the brain at rest.
View Article and Find Full Text PDFNetw Neurosci
December 2024
Department of Cognition, Development and Education Psychology, University of Barcelona, Barcelona, Spain.
Memories are thought to use coding schemes that dynamically adjust their representational structure to maximize both persistence and efficiency. However, the nature of these coding scheme adjustments and their impact on the temporal evolution of memory after initial encoding is unclear. Here, we introduce the Segregation-to-Integration Transformation (SIT) model, a network formalization that offers a unified account of how the representational structure of a memory is transformed over time.
View Article and Find Full Text PDFFront Neurol
December 2024
CLAIM - Charité Lab for AI in Medicine, Charité Universitätsmedizin Berlin, Corporate Member of Freie Universität Berlin, Humboldt-Universität zu Berlin and Berlin Institute of Health, Berlin, Germany.
Introduction: Radiological scores used to assess the extent of subarachnoid hemorrhage are limited by intrarater and interrater variability and do not utilize all available information from the imaging. Image segmentation enables precise identification and delineation of objects or regions of interest and offers the potential for automatization of score assessments using precise volumetric information. Our study aims to develop a deep learning model that enables automated multiclass segmentation of structures and pathologies relevant for aneurysmal subarachnoid hemorrhage outcome prediction.
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December 2024
Department of Orthopedic Surgery, Yonsei University College of Medicine, Seoul, South Korea.
The unique saddle articulation of the trapeziometacarpal joint allows for a wide range of motion necessary for routine function of the thumb. Inherently unstable characteristics of the joint can lead painful instability. In this study, we modified a surgical dorsal ligament reconstruction technique for restoring trapeziometacarpal joint stability.
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December 2024
School of Mechanical Engineering, Qilu University of Technology (Shandong Academy of Sciences), Jinan, 250353, China.
Microtextured microneedles are tiny needle-like structures with micron-scale microtextures, and the drugs stored in the microtextures can be released after entering the skin to achieve the effect of precise drug delivery. In this study, the skin substitution model of Ogden's hyperelastic model and the microneedle array and microtexture models with different geometrical parameters were selected to simulate and analyse the flow of the microtexture microneedle arrays penetrating the skin by the finite-element method, and the length of the microneedles was determined to be 200 μm, the width 160 μm, and the value of the gaps was determined to be 420 μm. A four-pronged cone was chosen as the shape of microneedles, and a rectangle was chosen as the shape of the drug-carrying microneedle.
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