Ventricular tachycardia after naloxone administration in an adolescent.

Am J Emerg Med

Division of Pediatric Critical Care Medicine, Department of Pediatrics, Massachusetts General Hospital for Children, Harvard Medical School, 175 Cambridge Street, 5(th) Floor, Boston, MA 02114, United States; Department of Pediatrics, Massachusetts General Hospital for Children, Harvard Medical School, 175 Cambridge Street, 5(th) Floor, Boston, MA 02114, United States. Electronic address:

Published: November 2021

AI Article Synopsis

  • Naloxone is a safe medicine often given in hospitals to help people who are confused or have weird symptoms.
  • Sometimes, it has caused a heart problem called ventricular tachycardia in adults who have used certain drugs before, but this hasn't happened in kids without a drug history.
  • A 17-year-old boy had a heart issue after getting naloxone, even though he had no history of using those drugs, so doctors should be ready to help kids who might have heart problems after taking naloxone.

Article Abstract

Naloxone is a medication with a largely benign safety profile that is frequently administered in the emergency department to patients presenting with altered mental status. Ventricular tachycardia has been reported after naloxone administration in adult patients with prior use of opiate or sympathomimetic medications. However, no such reports exist in the pediatric population or in patients who have no known history of opiate or sympathomimetic medication use. We describe a case of ventricular tachycardia after naloxone administration in a 17-year-old male with no known prior use of opiate or sympathomimetic agents who presented to the emergency department with altered mental status of unknown etiology. Emergency physicians may wish to prepare for prompt treatment of ventricular arrythmias when administering naloxone to pediatric patients presenting with altered mental status.

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Source
http://dx.doi.org/10.1016/j.ajem.2021.05.083DOI Listing

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