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Two new physalins from L. var. (Mast.) Makino. | LitMetric

Two new physalins from L. var. (Mast.) Makino.

Nat Prod Res

Key Lab of Chemical Biology (MOE), School of Pharmaceutical Sciences, Cheeloo College of Medicine, Shandong University, Jinan, People's Republic of China.

Published: October 2022

Two new physalins, 7α-hydroxy-5-deoxy-4-dehydrophysalin IX () and 5-deoxy-4-dehydrophysalin IX (), together with six known compounds, luteolin (), luteolin-7--glucoside (), neoechinulin A (), 3-(4-hydroxy-3-methoxyphenyl)--(4-methylphenyl)-2-propenamide (), physalin D () and blumenol A () were isolated from L. var. (Mast.) Makino. Their structures were elucidated by NMR spectroscopic analysis, HR-ESI-MS, X-ray crystallographic data analysis and comparison with the known compounds. Among them, compounds and were isolated from the genus for the first time. Compound exhibited weak NAD(P)H: quinone reductase (QR) inducing activity.

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Source
http://dx.doi.org/10.1080/14786419.2021.1924713DOI Listing

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