A clear understanding of community response to government decisions is crucial for policy makers and health officials during the COVID-19 pandemic. In this study, we document the determinants of implementation and compliance with stay-at-home orders in the USA, focusing on trust and social capital. Using cell phone data measuring changes in non-essential trips and average distance traveled, we find that mobility decreases significantly more in high-trust counties than in low-trust counties after the stay-at-home orders are implemented, with larger effects for more stringent orders. We also provide evidence that the estimated effect on post-order compliance is especially large for confidence in the press and governmental institutions, and relatively smaller for confidence in medicine and in science.
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http://dx.doi.org/10.1007/s00148-021-00848-z | DOI Listing |
Nat Commun
December 2024
College of Life Sciences, Inner Mongolia Agriculture University, Hohhot, Inner Mongolia, P. R. China.
Zika virus (ZIKV) infection can result in a birth defect of the brain called microcephaly and other severe fetal brain defects. ZIKV enters the susceptible host cells by endocytosis, which is mediated by the interaction of the envelope (E) glycoprotein with cellular surface receptor molecules. However, the cellular factors that used by the ZIKV to gain access to host cells remains elusive.
View Article and Find Full Text PDFJ Cell Biol
March 2025
Guangzhou National Laboratory , Guangzhou, China.
β-coronavirus rearranges the host cellular membranes to form double-membrane vesicles (DMVs) via NSP3/4, which anchor replication-transcription complexes (RTCs), thereby constituting the replication organelles (ROs). However, the impact of specific domains within NSP3/4 on DMV formation and RO assembly remains largely unknown. By using cryogenic-correlated light and electron microscopy (cryo-CLEM), we discovered that the N-terminal and C-terminal domains (NTD and CTD) of SARS-CoV-2 NSP3 are essential for DMV formation.
View Article and Find Full Text PDFOpen Vet J
November 2024
Pasteur Institute of Tunis, Tunis, Tunisia.
Background: Since 2012, the northeast region of Tunisia has witnessed an increase in dog rabies cases, indicating a concerning emergence of the disease. Previous studies have indicated the widespread nature of rabies in northern Tunisia. However, there remains a lack of comprehensive understanding regarding the associated risk factors.
View Article and Find Full Text PDFPol J Vet Sci
December 2024
Department of Customs Inspection and Quarantine, Shanghai Customs College, Shanghai, China.
, commonly known as , is a critical zoonotic pathogen that significantly reduces milk yield and product quality and poses a significant risk to public health. Although is increasingly recognised as a principal agent causing milkborne infections, research dedicated to this pathogen in dairy cattle has been less extensive than that of other pathogens. This study aimed to examine the antibiotic resistance profiles of derived from dairy cows and assess its pathogenicity using validated in vivo models.
View Article and Find Full Text PDFFront Plant Sci
December 2024
Department of Agriculture, Food and Environment, University of Pisa, Pisa, Italy.
(FD) is a major grapevine disease in Europe, despite the quarantine status of its causal agent [FD phytoplasma (FDp)] and the mandatory monitoring and vector control practices. As alarming FD epidemic outbreaks continue to appear in Tuscany (Central Italy), a 4-year survey was carried out in the main wine-growing areas of the region, where FD presence was investigated in both primary and secondary FDp hosts and vectors, i.e.
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