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Evaluation of Three Immunoassays for the Rapid Detection of SARS-CoV-2 antigens. | LitMetric

Evaluation of Three Immunoassays for the Rapid Detection of SARS-CoV-2 antigens.

Diagn Microbiol Infect Dis

Department of Experimental and Clinical Medicine, University of Florence, Florence, Italy; Microbiology and Virology Unit, Careggi University Hospital, Florence, Italy. Electronic address:

Published: October 2021

AI Article Synopsis

  • Three different tests for detecting SARS-CoV-2 antigens in nasopharyngeal swabs were compared: Lumipulse® G (LPG), STANDARD F (STF), and AFIAS COVID-19 (AFC).
  • When tested against the standard RT-PCR method, the sensitivity of these tests varied significantly, with LPG showing the highest sensitivity at 87.9%, while AFC and STF had lower sensitivities at 37.5% and 35.7%, respectively.
  • All three assays demonstrated high specificity, maintaining over 95% accuracy in correctly identifying non-infected individuals.

Article Abstract

Three assays for SARS-CoV-2 antigen detection in nasopharyngeal swabs (Lumipulse® G SARS-CoV-2 Ag [LPG], STANDARD F COVID-19 Ag FIA [STF] and AFIAS COVID-19 Ag [AFC] were evaluated. Compared to RT-PCR, LPG, AFC and STF showed a variable sensitivity (87.9%, 37.5%, and 35.7%, respectively) and an overall high specificity (> 95%).

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Source
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC8137375PMC
http://dx.doi.org/10.1016/j.diagmicrobio.2021.115434DOI Listing

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