Adolescent depression is linked to adult ill-health and functional impairment, but recent research suggests that individual/contextual factors might account for this association. This study aimed to test whether the clinical heterogeneity of adolescent depression is related to marginalization from the labor market across early to middle adulthood. Data were drawn from the Uppsala Longitudinal Adolescent Depression Study, a community-based cohort initially assessed with structured clinical interviews at age 16-17. The cohort (n = 321 depressed; n = 218 nondepressed) was followed up after 2+ decades through linkage to nationwide population-based registries. Outcomes included consecutive annual data on unemployment, work disability, social welfare recipiency, and a composite marginalization measure, spanning from age 21 to 40. Longitudinal associations were examined using logistic regression analysis in a generalized estimating equations modeling framework. Subsequent depressive episodes and educational attainment in early adulthood were explored as potential pathways. The results showed that adolescent depression was associated with adult marginalization outcomes, but the strength of association varied across depressed subgroups. Adolescents with persistent depressive disorder had higher odds of all outcomes, including the composite marginalization measure (adjusted OR = 2.0, 95% CI = 1.4-2.7, p < 0.001), and this was partially (31%) mediated by subsequent depressive episodes in early adulthood. Exploratory moderation analysis revealed that entry into tertiary education mitigated the association with later marginalization, but only for adolescents with episodic major depression. In conclusion, the risk for future labor market marginalization is elevated among depressed adolescents, particularly those presenting with persistent depressive disorder. Targeted interventions seem crucial to mitigate the long-lasting impact of early-onset depression.
Download full-text PDF |
Source |
|---|---|
| http://www.ncbi.nlm.nih.gov/pmc/articles/PMC9666342 | PMC |
| http://dx.doi.org/10.1007/s00787-021-01825-3 | DOI Listing |
Publication Analysis
Top Keywords
Similar Publications
Neuropsychiatric Outcomes in Children and Adolescents with Perinatally Acquired HIV: A Systematic Review and Meta Analysis.
J Acquir Immune Defic Syndr
January 2025
Department of Psychiatry, University of Oxford, Oxford OX3 7JX, UK.
Objective: The objective of this study is to define the neuropsychiatric challenges including developmental delay, cognitive impairment and psychiatric illness faced by children with perinatally acquired HIV.
Data Sources: Nine databases were searched on 30/05/2023: MEDLINE, Embase, and PsycINFO (all via Ovid SP); CINAHL and Child Development and Adolescent Studies (via EBSCO); the Web of Science Core Collection; Scopus; ProQuest Dissertations and Theses Global; and WHO Global Index Medicus. No limits were applied.
Network analysis of intergenerational transmission of psychopathological symptom among adolescents: A cross-sectional study.
J Fam Psychol
January 2025
Department of Psychiatry, Renmin Hospital of Wuhan University.
The intergenerational transmission of psychopathology has been well documented, but limited studies have examined the link at the symptomatic level accounting for these associations. This study aimed to identify the central symptoms that bridge adolescents and parental psychopathological symptoms and the specific symptom pathways by using a novel network approach. From September to October 2021, a cross-sectional study was conducted in Wuhan, China.
View Article and Find Full Text PDFPsychiatric morbidity among SARS and COVID-19 survivors at 30 months post-infection.
East Asian Arch Psychiatry
December 2024
Department of Psychiatry, United Christian Hospital, Hong Kong SAR, China.
Background: Severe acute respiratory syndrome (SARS) and COVID-19 are both highly infectious diseases that cause severe respiratory illness. This study aimed to compare survivors of SARS and COVID-19 and identify factors associated with long-term psychiatric comorbidities.
Methods: This was a retrospective cohort study of adult Chinese survivors of SARS and COVID-19 who had been admitted to the United Christian Hospital, Hong Kong.
Factors associated with habitual drug use among adolescents: A secondary data analysis.
Asian Nurs Res (Korean Soc Nurs Sci)
December 2024
College of Nursing, Pusan National University. Electronic address:
Purpose: Drug use during adolescence can have lasting health consequences, and understanding the factors that contribute to drug use is essential for effective prevention. This study aimed to identify the factors influencing habitual drug use among South Korean adolescents. It employed Bronfenbrenner's ecological model to examine personal, familial, school-related, and social factors.
View Article and Find Full Text PDFAssociation between autism diagnosis rates and adolescent depression: A population-based study in Sweden.
Psychiatry Res
December 2024
Centre for Psychiatry Research, Department of Clinical Neuroscience, Karolinska Institutet, Stockholm Health Care Services, Karolinska University Hospital, Region Stockholm, Stockholm SE-171 76, Sweden; Stockholm Health Care Services, Region Stockholm, Sweden.
Article Synopsis
- The study investigates the link between rising autism-related disorder (ASD-R) diagnosis rates and decreasing major depressive disorder (MDD) rates in Swedish adolescents aged 15-19 from 2008 to 2022.
- Results show a significant inverse relationship, with higher ASD-R diagnoses correlating to lower MDD rates, particularly in males.
- While causal conclusions are limited due to the study's observational design, the findings suggest a need for more comprehensive research on the complex interplay between these disorders.
Want AI Summaries of new PubMed Abstracts delivered to your In-box?
Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!