Carcinoma showing thymus-like elements (CASTLE) is an extremely rare malignant tumor of the thyroid gland and soft tissues of the neck with favorable prognosis. Histological features of the CASTLE are similar to thymic carcinoma, and it is assumed that it arises from the ectopic thymic tissue or the remnants of branchial pouches. The optimal treatment strategy is still uncertain because of the rarity of the tumor. The mainstay of treatment is surgery. The role of other modalities is unclear. We present a case report of a patient with locally advanced CASTLE of the thyroid gland who was not suitable for surgery and underwent radical radiotherapy with subsequent achievement of complete remission. We also present a literature review.
Download full-text PDF |
Source |
|---|---|
| http://dx.doi.org/10.1007/s00066-021-01800-6 | DOI Listing |
Publication Analysis
Top Keywords
Similar Publications
The Genetic Causal Effect of Autoimmune Diseases on pan-Cancers: Evidence from Mendelian Randomization.
J Cancer
January 2025
Department of Spinal Surgery, Tianjin Union Medical Center, Tianjin, China.
Whether autoimmune diseases caused any effects on the risk of cancers remained yet clarified. This study aimed to investigate the causal effect of autoimmune diseases on pan-cancers through mendelian randomization (MR) analysis. The GWAS summary datasets of 10 autoimmune diseases were derived from the IEU or UK biobank website.
View Article and Find Full Text PDFA Two-Way Mendelian Randomization Analysis on the Link between Thyroid Activity Function and Coronary Atherosclerosis.
Rev Cardiovasc Med
December 2024
Department of Cardiothoracic Surgery, The First Affiliated Hospital of Chongqing Medical University, 400016 Chongqing, China.
Introduction: Coronary atherosclerosis serves as the primary pathological etiology underlying coronary artery disease (CAD). Thyroid hormones show potential as risk factors, aside from the main standard modifiable cardiovascular risk factors (SMuRFs). This research seeks to elucidate the link between thyroid activity and coronary atherosclerosis.
View Article and Find Full Text PDFThyroid function, autoimmunity, thyroid volume, and metabolic profile in people with Hashimoto thyroiditis.
BMC Endocr Disord
December 2024
Basic and Clinical Immunology, Department of Pathology, Faculty of Medicine, University of Porto, Porto, Portugal.
Background: Hashimoto's thyroiditis (HT) is associated with high cardiovascular risk. Thyroid volume has a notable dispersion of values in these patients. This study aims to clarify the association between thyroid antibodies, thyroid morphology, insulin resistance, and lipid profile in patients with HT.
View Article and Find Full Text PDFRemoval of a parotid foreign body by endoscopic surgery-a case report.
Int J Surg Case Rep
December 2024
Department of Thyroid, Head, Neck and Maxillofacial Surgery, the Third Hospital of Mianyang, Sichuan Mental Health Center, Mianyang, Sichuan 621000, PR China. Electronic address:
Backgrounds: Parotid foreign bodies are not common. The majority of cases are caused by trauma. The clinical presentation, symptoms, and duration of discomfort vary among patients and may be challenging to treat.
View Article and Find Full Text PDFThe impact of exposure to phthalates in thyroid function of children and adolescents: a systematic review.
Eur J Pediatr
December 2024
Department of Biomedicine - Pharmacology and Therapeutics Unit, Faculty of Medicine, University of Porto, Porto, Portugal.
Phthalic acid esters, or phthalates, are plasticizers commonly used in the plastics industry and they are known for their endocrine-disrupting effects. Numerous epidemiological studies have been conducted to evaluate the effects of phthalate exposure on thyroid function, both in adults and children. However, there is still considerable debate surrounding this issue.
View Article and Find Full Text PDFWant AI Summaries of new PubMed Abstracts delivered to your In-box?
Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!