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Radiological, clinical, and molecular analyses reveal distinct subtypes of butterfly glioblastomas affecting the prognosis.
Neurooncol Adv
October 2024
Department of Neurosurgery, Kitasato University School of Medicine, Sagamihara, Kanagawa, Japan.
Article Synopsis
- Glioblastoma (GB) is highly invasive, and the study investigates the origins and molecular characteristics of butterfly glioblastoma (bGB) by analyzing a cohort of 34 bGB patients alongside others from public datasets.
- The results show that bGB can arise from two distinct origins—corpus callosum (CC) and cerebral hemisphere—with unique molecular mutations and prognostic implications, particularly identifying the CC-type as having worse survival outcomes.
- The study emphasizes the need for further research to understand the clinical significance and differences between the identified bGB subtypes to enhance treatment strategies and patient care.
Military training areas can host important biodiversity, due to the preservation of diverse, nutrient-poor historical cultural landscapes and an insect-friendly disturbance regime. In Europe, many training areas were abandoned after the end of the cold war in 1991 and the withdrawal of the Allied and Soviet forces. Many of these are now protected areas, and current management strategies vary from rewilding to active habitat management such as grazing or mowing.
View Article and Find Full Text PDFLarval growth rate is not a major determinant of adult wing shape and eyespot size in the seasonally polyphenic butterfly .
PeerJ
October 2024
School of Biological and Behavioural Sciences, Queen Mary University London, London, United Kingdom.
Background: Insects often show adaptive phenotypic plasticity where environmental cues during early stages are used to produce a phenotype that matches the environment experienced by adults. Many tropical satyrine butterflies (Nymphalidae: Satyrinae) are seasonally polyphenic and produce distinct wet- and dry-season form adults, providing tight environment-phenotype matching in seasonal environments. In studied Mycalesina butterflies, dry-season forms can be induced in the laboratory by growing larvae at low temperatures or on poor food quality.
View Article and Find Full Text PDFComparing New Smartphone-Connected Handheld Ultrasound Device vs. Traditional Ultrasound in Vitreo-Retinal Disease Diagnosis.
Diagnostics (Basel)
September 2024
Department of Ophthalmology, University of Catania, 95123 Catania, Italy.
(1) Background: Ocular emergencies account for 1.5-3% of emergency department (ED) visits and require urgent diagnosis to prevent serious complications. Ultrasonography is a crucial, non-invasive diagnostic tool for these conditions but traditionally lacks portability and integration with modern electronic smart devices.
View Article and Find Full Text PDFVACTERL Association in a Fetus With a Normal Genetic Profile.
Cureus
July 2024
Pathology and Laboratory Medicine, Shri B.M. Patil Medical College, Hospital & Research Centre, BLDE (Deemed to be University), Vijayapura, IND.
Article Synopsis
- VACTERL association is a grouping of birth defects affecting various organ systems, and a diagnosis requires presence of at least three anomalies without any other identifiable patterns.
- A case study involves a pregnant woman in her 20s whose fetus was found to have multiple abnormalities during prenatal scans, leading to the decision to terminate the pregnancy due to poor prognosis.
- Post-abortion autopsy revealed significant defects, including club feet and heart anomalies, demonstrating the value of fetal autopsies for confirming diagnoses and understanding underlying causes in similar situations.
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