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Two new sphingolipids from the stem bark of . | LitMetric

commonly known as Bang Bali in Bali-Nguemba, Cameroon is used in traditional medicine against various diseases. The leaves and stem bark extracts were subjected to silica gel and Sephadex LH column chromatography to yield pure compounds. The structures of the compounds were determined by detail analysis of NMR and Mass spectroscopic data and by comparison with data reported in the literature. Amongst the isolates, were two new sphingolipids: synsepaloside B (), synsepaloside C (), and five known compounds: (+)-catechin (), (-)-epicatechin (), myricitrin (), triacontanol (), and aurantiamide acetate (). Compounds - were screened for their antibacterial and anti-yeast activities on several microorganisms. All the tested compounds exhibited weak antibacterial (MIC 200 μg/mL) and anti-yeast (MIC > 200 μg/mL) activities as compared to standard: ciprofloxacin 0.468 < MIC >0.234 μg/mL and fluconazole MIC = 0.05 μg/mL, respectively.

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Source
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC8202346PMC
http://dx.doi.org/10.1016/j.bbrep.2021.101014DOI Listing

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