We describe a case of a poorly controlled diabetic patient with left endogenous panophthalmitis with orbital cellulitis and positive ocular culture of with negative systemic workup and rare clinical presentation. Was misdiagnosed and mismanaged as acute angle-closure glaucoma. Despite medical treatment with intravenous antibiotics, the patient required evisceration of the left eye as a result of the delay in diagnosis and treatment. A high index of suspicion for endogenous endophthalmitis and awareness of the proper workup and different clinical presentations is needed to avoid vision and life-threatening consequences.
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http://dx.doi.org/10.7759/cureus.15103 | DOI Listing |
Indian J Ophthalmol
October 2024
Department of Clinical and Public Health Research, CL Gupta Eye Institute, Ram Ganga Vihar, Phase II (Ext), Moradabad, Uttar Pradesh, India.
Nepal J Ophthalmol
July 2023
Government Medical College and Hospital, Chandigarh, Punjab, India.
Background: Endogenous endophthalmitis refers to the intraocular infection resulting via haematogenous spread from the distant foci. Dengue is an important health problem in India with varied ophthalmic manifestations either due to viremia, immunologic phenomenon, or haemorrhagic tendency.
Case: We report an unusual presentation of endogenous endophthalmitis as fulminant orbital cellulitis in a young adult patient having a history of dengue fever.
J Infect Chemother
January 2025
Advanced Eye Centre, Post Graduate Institute of Medical Education and Research, Chandigarh, 160012, India.
An eleven year old male reported a ten-day history of unilateral pain, redness, and sudden loss of vision. Ophthalmic examination revealed panophthalmitis that did not respond to conventional intravenous antibiotics, and systemic deterioration raised suspicion of a fungal aetiology. However, the worsening of the ocular condition from panophthalmitis to orbital cellulitis upon commencement of amphotericin B suggests the presence of a fastidious microorganism.
View Article and Find Full Text PDFJ Ophthalmic Inflamm Infect
March 2024
Department of Ophthalmology, Alfred Hospital, Melbourne, Australia.
Purpose: To report a case of endogenous Lomentospora prolificans endophthalmitis treated with the novel antifungal agent Olorofim.
Case Report: A 57-year-old man developed disseminated Lomentospora prolificans with right endophthalmitis on the background of immunosuppression following lung transplantation for interstitial lung disease. He was treated with early vitrectomy, intravitreal voriconazole, and systemic Olorofim, voriconazole and terbinafine.
Cureus
October 2023
Ophthalmology, Kulliyyah of Medicine, International Islamic University Malaysia, Kuantan, MYS.
Panophthalmitis is a severe ocular condition that can lead to devastating outcomes, such as evisceration, if not promptly treated. It typically originates endogenously, with urinary tract infection being a common primary source of infection. This report describes a rare case of a 61-year-old Malay patient with left eye panophthalmitis.
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