Non-C. difficile Clostridioides Bacteremia in Intensive Care Patients, France.

Usually responsible for soft tissue infections, species can also cause bacteremia, life-threatening infections often requiring intensive care unit (ICU) admission. We conducted a multicenter retrospective study to investigate bacteremia in ICUs to describe the clinical and biologic characteristics and outcomes in critically ill patients. We identified 135 patients with bacteremia, which occurred almost exclusively (96%) in patients with underlying conditions. Septic shock and digestive symptoms were the hallmarks of bacteremia in the ICU. We identified 16 different species of , among which accounted for 31% of cases. Despite the high sensitivity of to common antimicrobial drugs, mortality rates were high: 52% for ICU patients and 71% overall at 3 months. In multivariate analysis, the most important factor associated with increased risk for death was the presence of hemolysis. bacteremia often leads to multiple organ failures, which have high mortality rates.