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Reactive Oxygen Species Resistive Redox Mediator in Lithium-Oxygen Batteries.
Adv Mater
January 2025
School of Energy and Chemical Engineering, Ulsan National Institute of Science and Technology, Ulsan, 44919, Republic of Korea.
The utilization of redox mediators (RMs) in lithium-oxygen batteries (LOBs) has underscored their utility in high overpotential during the charging process. Among the currently known RMs, it is exceptionally challenging to identify those with a redox potential capable of attenuating singlet oxygen (O) generation while resisting degradation by reactive oxygen species (ROS), such as O and superoxide (O ). In this context, computational and experimental approaches for rational molecular design have led to the development of 7,7'-bi-7-azabicyclo[2.
View Article and Find Full Text PDFSelf-assembled eumelanin nanoparticles enhance IFN-I activation and cilia-driven intercellular communication to defend against Tulane virus, a human norovirus surrogate.
Biomater Sci
January 2025
Department of Food Science & Technology, Faculty of Science, National University of Singapore, 117546, Singapore.
Norovirus (NoV) infection is a leading cause of gastroenteritis and poses global health threats, with increasing incidence reported in immunocompromised individuals, which is further exacerbated by the globalization of the food industry. Eumelanin has demonstrated its potential in antiviral treatments, but its role in preventing viral infections remains underexplored. Therefore, in this study, we investigated the antiviral properties and potential mechanisms of self-assembled eumelanin nanoparticles (EmNPs) against Tulane virus (TuV), a surrogate with a similar infection mechanism to NoVs.
View Article and Find Full Text PDFObjectives: To understand the competitive position of the UK in comparison to Europe and the USA for haematological cancer clinical research.
Design: Using commercially available databases, clinical trial numbers, their effectiveness and publication outputs were evaluated in two analyses: a macrodevelopment and a research activity and performance analysis.
Data Sources: The following databases were used for this analysis: Organisation for Economic Co-operation and Development, Thomson Reuters Incidence and Prevalence, the Cortellis Clinical Trial Intelligence, the Clarivate Cortellis Innography Patent Intelligence, Thomson-Reuters Cortellis Regulatory Intelligence, Thomson Reuters Web of Science and data from the Centre for Medicine Research (CMR).
Improving surgical quality of care: learning from 8,331 surgical medical malpractice cases.
Front Med (Lausanne)
December 2024
School of Nursing, Southwest Medical University, Luzhou, China.
Objective: This study aimed to analyze the characteristics of surgical litigation cases and the risk factors that contribute to catastrophic compensation.
Methods: We downloaded and retrieved all cases related to surgical litigation cases from the China Jufaanli Database between 2008 and 2023. Multivariate logistic regression analysis was employed to identify independent risk factors that may contribute to catastrophic compensation.
Evaluating Personal Safety Within the LGBTQIA+ Campus Community: A Needs Assessment.
J Forensic Nurs
December 2024
Author Affiliation: College of Nursing, Miami University.
Background: Violence against sexual and gender minorities is a significant concern on university campuses.
Methods: A needs assessment self-report survey was administered to LGBTQIA+ university campus community members to assess perceptions of vulnerability, interest in, and beliefs related to personal safety/self-defense (PS/SD) training at a public Midwestern university.
Results: Forty-three LGBTQIA+ campus community members responded to the survey.
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