Concurrent passive mode-locked and self-Q-switched operation of laser devices is modeled using the complex cubic-quintic Ginzburg-Landau equation. Experimental observations use a passively mode-locked fiber ring laser with a waveguide array as a fast saturable absorber. The shape of each individual self-Q-switched pulse and the periodic trains of pairs of such pulses are in a good qualitative agreement with the numerical results.
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http://dx.doi.org/10.1103/PhysRevLett.126.224101 | DOI Listing |
Cureus
November 2024
Department of Orthopaedic Surgery, King George's Medical University, Lucknow, IND.
Introduction Precise implant positioning, particularly a well-balanced posterior tibial slope (PTS), is crucial for the success of total knee arthroplasty (TKA) because it enhances sagittal plane stability and significantly influences knee motion patterns. The long-term impact of tibial slope on active and passive range of motion (ROM) still needs to be studied, despite ROM's crucial role in patient contentment. This study examined the relationship between tibial slope and active and passive ROM following TKA, with a follow-up period of at least three months.
View Article and Find Full Text PDFJ Psychiatr Res
December 2024
University of Groningen, University Medical Center Groningen, University Center for Psychiatry, Hanzeplein 1, PO Box 30.001, 9700 GZ, Groningen, the Netherlands.
Background: Symptom severity and social functioning are important outcomes after first episode psychosis (FEP), yet current evidence about associations between them is inconsistent and lacks (subclinical) momentary insights.
Methods: The current Ecological Momentary Assessment (EMA) study was conducted in 58 people in remission from FEP, as part of the HAMLETT (Handling Antipsychotic Medication: Long-term Evaluation of Targeted Treatment) trial. At baseline, participants were prompted to report momentary mental states and social context 10x/day for eight consecutive days, including psychotic experiences (PEs), motivation/drive and negative affect, that may indicate proxies of (subclinical) psychotic, negative and general affective symptoms, respectively.
Acta Biomater
December 2024
Guangdong Provincial Key Laboratory of New Drug Screening, Guangzhou Key Laboratory of Drug Research for Emerging Virus Prevention and Treatment, NMPA Key Laboratory for Research and Evaluation of Drug Metabolism, Guangdong-Hong Kong-Macao Joint Laboratory for New Drug Screening, School of Pharmaceutical Sciences, Southern Medical University, Guangzhou, Guangdong 510515, China. Electronic address:
Immunotherapy has emerged as a highly promising strategy in the realm of cancer treatment, wherein immunogenic cell death (ICD) is considered a potential trigger for anti-tumor immunity by inducing adaptive immunity to dying cell antigens. This process is often accompanied by the exposure, active secretion, or passive release of a large number of damage-associated molecular patterns (DAMPs), which activate dendritic cells (DCs) and enhance their antigen-presenting capacity. Subsequently, it promotes the recruitment and activation of cytotoxic T lymphocytes, ultimately leading to tumor growth inhibition.
View Article and Find Full Text PDFMalar J
December 2024
Groupe de Recherche Action en Santé (GRAS), Ouagadougou, West Africa, Burkina Faso.
Background: In malaria vaccine clinical trials, immune responses after vaccination may be compromised due to immunosuppression caused by concurrent Plasmodium falciparum infection. This has a direct effect on the protective efficacy of the vaccine being evaluated. Therefore, parasite clearance prior to vaccination is being considered.
View Article and Find Full Text PDFJ Environ Manage
December 2024
Dept. of Civil Engineering, Indian Institute of Technology (IIT) Bombay, Mumbai, 400076, Maharashtra, India. Electronic address:
Active saltwater intrusion (ASWI) accelerates and intensifies salinization due to buoyancy force-induced density differences and concurrent inland fresh groundwater flow. This study investigates saline groundwater (SGW) pumping as a remediation technique for ASWI through experimental and field-scale analyses in a layered aquifer system characterised by diminishing permeability with depth. Experiments demonstrated that higher permeability layers reduced length of intrusion (Ltoe) whereas lower permeability layers restricted vertical displacement.
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