How Activity Landscapes Polarize Microswimmers without Alignment Forces.

Phys Rev Lett

Peter Debye Institute for Soft Matter Physics, Leipzig University, 04103 Leipzig, Germany.

Published: June 2021

Active-particle suspensions exhibit distinct polarization-density patterns in activity landscapes, even without anisotropic particle interactions. Such polarization without alignment forces is at work in motility-induced phase separation and betrays intrinsic microscopic activity to mesoscale observers. Using stable long-term confinement of a single thermophoretic microswimmer in a dedicated force-free particle trap, we examine the polarized interfacial layer at a motility step and confirm that it does not exert pressure onto the bulk. Our observations are quantitatively explained by an analytical theory that can also guide the analysis of more complex geometries and many-body effects.

Download full-text PDF

Source
http://dx.doi.org/10.1103/PhysRevLett.126.228001DOI Listing

Publication Analysis

Top Keywords

activity landscapes
8
alignment forces
8
landscapes polarize
4
polarize microswimmers
4
microswimmers alignment
4
forces active-particle
4
active-particle suspensions
4
suspensions exhibit
4
exhibit distinct
4
distinct polarization-density
4

Similar Publications

Unveiling the role of PANoptosis-related genes in breast cancer: an integrated study by multi-omics analysis and machine learning algorithms.

Breast Cancer Res Treat

January 2025

Department of Breast Surgery, Thyroid Surgery, Huangshi Central Hospital, Affiliated Hospital of Hubei Polytechnic University, No.141, Tianjin Road, Huangshi, 435000, Hubei, China.

Background: The heterogeneity of breast cancer (BC) necessitates the identification of novel subtypes and prognostic models to enhance patient stratification and treatment strategies. This study aims to identify novel BC subtypes based on PANoptosis-related genes (PRGs) and construct a robust prognostic model to guide individualized treatment strategies.

Methods: The transcriptome data along with clinical data of BC patients were sourced from the TCGA and GEO databases.

View Article and Find Full Text PDF

Purpose: MAP2K1/MEK1 mutations are potentially actionable drivers in cancer. MAP2K1 mutations have been functionally classified into three groups according to their dependency on upstream RAS/RAF signaling. However, the clinical efficacy of mitogen-activated protein kinase (MAPK) pathway inhibitors (MAPKi) for MAP2K1-mutant tumors is not well defined.

View Article and Find Full Text PDF

Most diffuse large B-cell lymphoma (DLBCL) patients treated with immunotherapies such as bispecific antibodies (BsAb) or chimeric antigen receptor (CAR) T cells fail to achieve durable treatment responses, underscoring the need for a deeper understanding of mechanisms that regulate the immune environment and response to treatment. Here, an integrative, multi-omic approach was applied to multiple large independent datasets in order to characterize DLBCL immune environments, and to define their association with tumor cell-intrinsic genomic alterations and outcomes to CD19-directed CAR T-cell and CD20 x CD3 BsAb therapies. This approach effectively segregated DLBCLs into four immune quadrants (IQ) defined by cell-of-origin and immune-related gene set expression scores.

View Article and Find Full Text PDF

Recent analyses of social media activity indicate that outgroup animosity drives user engagement more than ingroup favoritism, with content that derogates the outgroup tending to generate more viral responses online. However, it is unclear whether those findings are due to most people's underlying preferences or structural features of the social media landscape. To address this uncertainty, we conducted three experimental studies ( = 609) to examine how intended impact (ingroup favoritism/outgroup derogation) influences intentions to share both true and false news posts among U.

View Article and Find Full Text PDF

Freshwater ecosystems face significant threats, including pollution, habitat loss, invasive species, and climate change. To address these challenges, management strategies and restoration efforts have been broadly implemented. Across Europe, such efforts have resulted in overall improvements in freshwater biodiversity, but recovery has stalled or failed to occur in many localities, which may be partly caused by the limited dispersal capacity of many species.

View Article and Find Full Text PDF

Want AI Summaries of new PubMed Abstracts delivered to your In-box?

Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!