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Objective: We investigate the relationship between sarcopenia components and depression in geriatric outpatients, considering the effects of potential confounding factors.
Methods: Adults ≥60 years of age were selected from outpatient clinics. Muscle strength was assessed using handgrip strength (HGS) measured using a hydraulic hand dynamometer and chair stand test (CSST). Physical performance was evaluated by usual gait speed (UGS), nutritional status, and frailty were screened by mini-nutritional assessment (MNA) questionnaire and FRAIL scale. Depression was diagnosed through a psychiatric interview and the administration of the Geriatric Depression Scale (GDS).
Results: Participants with depression were similar to participants without depression regarding age ( = .055), education ( = .095), frailty ( = .857), and HGS scores ( = .053). The group with depression had longer CSST duration ( = .023), slower UGS ( = .027), and more malnutrition ( = .001). Multivariate regression analysis revealed that only the malnutrition was independently associated factor with depression after adjusting for confounding factors.
Conclusions: Depression is associated with malnutrition and some components of sarcopenia in geriatric outpatients. Our results revealed that sarcopenia might be associated with depression through malnutrition. If malnutrition lasts for a long time, sarcopenia may become evident in the later stages of depression.
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| http://dx.doi.org/10.1080/13685538.2021.1936482 | DOI Listing |
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