Foveal reorganization after treatment of acute foveal toxoplasmic retinochoroiditis.

J Ophthalmic Inflamm Infect

Eye Research Center, Khatam-al-Anbia Eye Hospital, Mashhad University of Medical Sciences, Qarani Blvd, Mashhad, 9195965919, Iran.

Published: June 2021

Purpose: To report a patient with impaired vision due to foveal involvement of toxoplasmic retinochoroiditis, who was successfully treated with intravitreal clindamycin and dexamethasone and oral therapy with azithromycin, trimethoprim-sulfamethoxazole, and prednisolone and led to successful visual and anatomic recovery.

Case Presentation: A 32-year-old man presented with three-day history of gradually decreasing visual acuity, redness, pain and photophobia of the right eye. Anterior chamber cellular reaction, vitritis and a white retinochoroiditis patch with adjacent retinal vasculitis in the fovea was suggestive of the toxoplasmic retinochoroiditis. He was treated with intravitreal clindamycin and dexamethasone injection followed by six-week regimen of azithromycin, trimethoprim-sulfamethoxazole, and prednisolone. In serial optical coherence tomography imaging, retinitis patch changed to cavitary foveal destruction. Fovea reorganized gradually, and visual acuity concurrently improved from counting finger 3 m to 20/25.

Conclusion: In foveal toxoplasmic retinochoroiditis lesions, timely treatment is associated with retinal reorganization and visual improvement.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC8215007PMC
http://dx.doi.org/10.1186/s12348-021-00246-2DOI Listing

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