AI Article Synopsis
- Increased abdominoplasty procedures worldwide necessitate effective pain management strategies to reduce opioid use post-surgery.
- A clinical trial was conducted comparing the effects of low-dose ketamine infusion versus morphine on postoperative pain in patients undergoing abdominoplasty.
- Results indicated that low-dose ketamine provided similar pain relief to morphine without significant side effects, suggesting it as a viable alternative for managing postoperative pain.
Article Abstract
Background: With the increased number of abdominoplasty all over the world, and the need to manage postoperative pain, it is a must to find proper and effective drugs to decrease opioid consumption in the postoperative period.
Objectives: In this double-blind randomized controlled clinical trial, we assumed that low-dose ketamine infusion will reduce the postoperative pain profile than the conventional method of morphine.
Methods: The scheduled patients for abdominoplasty under general anesthesia were recruited in two groups: group (K) with low-dose ketamine infusion intra-operatively (80 patients) and group (M) with morphine infusion intra-operatively (80 patients). Both groups were monitored intraoperatively and postoperatively for rescue doses of fentanyl, visual analogue scale (VAS), and side effects.
Results: There were no statistical differences between both groups regarding the fentanyl rescue doses intra- and postoperative with no remarkable side effects.
Conclusions: Low-dose ketamine has a useful analgesic effect in abdominoplasty similar to morphine without remarkable side effects, such as sedation or hallucinations.
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|---|---|
| http://www.ncbi.nlm.nih.gov/pmc/articles/PMC8207844 | PMC |
| http://dx.doi.org/10.5812/aapm.108469 | DOI Listing |
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