AI Article Synopsis

  • * The patient underwent a combined surgical procedure to remove both the kidney and gallbladder, revealing that the gallbladder mass was a solitary metastatic clear cell RCC.
  • * After three years of being disease-free, the patient developed a new renal mass, which illustrates the need for careful imaging review and consideration of other potential organ masses in RCC cases.

Article Abstract

Renal cell carcinoma (RCC) classically metastasizes to the lungs, bones, adrenals, lymph nodes, liver, and brain. RCC metastasis to the gallbladder is rare occurring in less than 1% of metastases. We present a case of a 60-year-old male who at initial diagnosis of his large left renal mass was incidentally found to have a gallbladder mass. He underwent simultaneous open radical nephrectomy and cholecystectomy with pathology confirming solitary metastatic clear cell RCC (ccRCC). The patient chose surveillance and was without evidence of disease for three years. At three years, imaging showed a 2 cm contralateral renal mass which was cryoablated percutaneously. This case demonstrates not only the importance of a thorough review of initial and surveillance imaging but also of maintaining a broad differential for other solid organ masses in the setting of a primary RCC of the kidney.

Download full-text PDF

Source
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC8202448PMC
http://dx.doi.org/10.7759/cureus.15007DOI Listing

Publication Analysis

Top Keywords

metastatic clear
8
clear cell
8
renal cell
8
cell carcinoma
8
renal mass
8
synchronous metastatic
4
cell
4
renal
4
cell renal
4
carcinoma gallbladder
4

Similar Publications

Symptom appraisal and help-seeking before a cancer diagnosis during pregnancy: a qualitative study.

Br J Gen Pract

January 2025

University of Surrey Faculty of Health and Medical Sciences, School of Health Sciences, Guildford, United Kingdom.

Background Estimated incidence of cancer diagnosis during or shortly after pregnancy is 1 in 1,000 women. Pregnancy can impact symptom appraisal and help-seeking for symptoms subsequently diagnosed as cancer. Little is known about the pathway to cancer diagnosis in pregnancy or delays that women can encounter.

View Article and Find Full Text PDF

Background: Intratumoral oncolytic herpes simplex virus 2-GM CSF (OH2) injection has shown safety and antitumor efficacy in patients with solid tumors. Here, we examined the safety and efficacy of OH2 as a single agent or in combination with HX008, an NMPA-approved PD-1 inhibitor, in locally advanced or metastatic sarcoma patients.

Methods: This multicenter, phase 1/2 trial enrolled patients with injectable sarcoma lesions, who had failed at least 1 or more lines of standard treatment.

View Article and Find Full Text PDF

Implications of a new clinical classification of acute myocardial infarction.

Eur Heart J Acute Cardiovasc Care

January 2025

BHF/University Centre for Cardiovascular Science, University of Edinburgh, Edinburgh, UK.

Aim: The diagnostic criteria for type 2 myocardial infarction identify a heterogenous group of patients with variable outcomes and no clear treatment implications. We aimed to determine the implications of a new clinical classification for myocardial infarction with more objective diagnostic criteria using cardiac imaging.

Methods: In a prospective cohort study, patients with type 2 myocardial infarction underwent coronary angiography and cardiac magnetic resonance imaging or echocardiography.

View Article and Find Full Text PDF

Unusual Cause of Ventricular Arrhythmia.

JACC Case Rep

January 2025

Department of Cardiovascular Magnetic Resonance, Hôpital Privé Jacques Cartier, Institut Cardiovasculaire Paris Sud, Massy, France.

Although relatively rare, cardiac metastases represent a significant clinical challenge because of their impact on cardiac function and overall patient prognosis. This case presents a rare and atypical presentation of a patient with ventricular arrhythmia revealing a metastatic cancer in the heart. A 59-year-old man with lung cancer was admitted for chest tightness and episodes of syncope.

View Article and Find Full Text PDF

Approach to Endocrine Hypertension: A Case-Based Discussion.

Curr Hypertens Rep

January 2025

Department of Endocrinology, Kasturba Medical College, Manipal Academy of Higher Education, Manipal, 576104, India.

Purpose Of Review: Hypertension remains a major chronic disease morbidity across the world, even in the twenty-first century, affecting ≈40% of the global population, adversely impacting the healthcare budgets in managing the high incidence of cardiovascular disease (CVD) complications and mortality because of elevated blood pressure (BP). However, evaluation and management of endocrine hypertension are not optimal in clinical practice. With three unique clinical case scenarios, we update the evidence base for diagnostic evaluation and management of endocrine hypertension in this review to inform appropriate day-to-day clinical practice decisions.

View Article and Find Full Text PDF

Want AI Summaries of new PubMed Abstracts delivered to your In-box?

Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!