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| http://dx.doi.org/10.1161/HYPERTENSIONAHA.121.17450 | DOI Listing |
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Association Between Cardiothoracic Fellows and Clinical and Financial Outcomes in Coronary Surgery.
J Surg Res
January 2025
Division of Cardiac Surgery, Department of Cardiovascular Sciences, East Carolina University, Greenville, North Carolina.
Introduction: Mounting financial pressures on academic institutions highlight the need to understand the effect on outcomes from trainee involvement in cardiac surgery. The purpose of this study is to examine the association between cardiothoracic fellows and clinical and financial outcomes in coronary artery bypass grafting (CABG).
Methods: Data for all patients from 2017 to 2022 at a single institution who underwent nonemergent, isolated, open CABG were included in the study, with patients grouped by whether there was fellow operative participation.
Case management in Emergency Care: Impact Evaluation of the CARED Program.
Int J Qual Health Care
January 2025
Department of Medicine, Johns Hopkins University, Baltimore, MD, USA.
Background: Hospitals face mounting pressure to reduce unplanned utilization amid rising healthcare demands from an aging population. The Case management for At-Risk patients in the Emergency Department (CARED) program is among the first ED transitional care strategies to focus on both frail older adults and Emergency Department (ED) re-attenders to reduce acute hospital utilization. This study aims to evaluate the effectiveness of the CARED program in reducing hospital (re)admissions and ED re-attendances within 30- and 60-days post-discharge.
View Article and Find Full Text PDFTransitioning to Green Discovery-Based Catalysis.
Chemistry
January 2025
Department of Chemistry, University of Vermont, 82 University Place, Burlington, VT 05405, USA.
Pressure is mounting to minimize the carbon footprint of chemical industry while increasing its sustainability. An argument is made that working from Green Chemistry principles during discovery-based catalysis results in effective chemistry and circumvents a need to "rediscover" chemical reactivity under sustainable conditions. Examples of comparative success in selected examples of hydrophosphination catalysis in various degrees of development are provided to support two main ideas: 1) Starting from more sustainable practices in chemical discovery is inertia in methodology that should be overcome, and 2) substantial challenges remain in catalysis for which sustainable solutions would positively impact other areas of chemistry.
View Article and Find Full Text PDFPreserving the Academic Mission Amid Radiologist Shortages and Financial Pressures.
AJR Am J Roentgenol
January 2025
Department of Diagnostic Radiology and Nuclear Medicine, University of Maryland School of Medicine, 22 S. Greene Street, Baltimore, MD 21201.
Academic radiology practices are navigating unprecedented operational and financial challenges, including a growing radiologist shortage, escalating imaging volumes, and mounting financial pressures driven by rising salaries, increasing practice expenses, and declining reimbursements. To address these challenges, academic department leaders must prioritize securing enhanced hospital professional service agreements and renegotiating outpatient imaging agreements. These strategic initiatives are essential to sustaining academic missions and ensuring long-term success.
View Article and Find Full Text PDFTwo-Level Spatially Localized Proximity Labeling for Cross-Biological-Hierarchy Measurement and Manipulation.
Angew Chem Int Ed Engl
January 2025
State Key Laboratory of Analytical Chemistry for Life Science, School of Chemistry and Chemical Engineering, Nanjing University, Nanjing, 210023, China.
Proximity labeling (PL) has emerged as a powerful technique for the in situ elucidation of biomolecular interaction networks. However, PL methods generally rely on single-biological-hierarchy control of spatial localization at the labeling site, which limits their application in multi-tiered biological systems. Here, we introduced another enzymatic reaction upstream of an enzyme-based PL reaction and targeted the two enzymes to markers indicating different biological hierarchies, establishing a two-level spatially localized proximity labeling (PL) platform for in situ molecular measurement and manipulation.
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