We study the approximation of two-layer compositions f(x)=g(ϕ(x)) via deep networks with ReLU activation, where ϕ is a geometrically intuitive, dimensionality reducing feature map. We focus on two intuitive and practically relevant choices for ϕ: the projection onto a low-dimensional embedded submanifold and a distance to a collection of low-dimensional sets. We achieve near optimal approximation rates, which depend only on the complexity of the dimensionality reducing map ϕ rather than the ambient dimension. Since ϕ encapsulates all nonlinear features that are material to the function f, this suggests that deep nets are faithful to an intrinsic dimension governed by f rather than the complexity of the domain of f. In particular, the prevalent assumption of approximating functions on low-dimensional manifolds can be significantly relaxed using functions of type f(x)=g(ϕ(x)) with ϕ representing an orthogonal projection onto the same manifold.
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http://dx.doi.org/10.1016/j.neunet.2021.06.004 | DOI Listing |
Sci Rep
January 2025
School of Air Traffic Management, Civil Aviation Flight University of China, Guanghan, 618300, China.
To address the challenges of high computational complexity and poor real-time performance in binocular vision-based Unmanned Aerial Vehicle (UAV) formation flight, this paper introduces a UAV localization algorithm based on a lightweight object detection model. Firstly, we optimized the YOLOv5s model using lightweight design principles, resulting in Yolo-SGN. This model achieves a 65.
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January 2025
Gastroenterology Department, The First Affiliated Hospital of Guangxi Medical University, Nanning, China.
To retrospectively develop and validate an interpretable deep learning model and nomogram utilizing endoscopic ultrasound (EUS) images to predict pancreatic neuroendocrine tumors (PNETs). Following confirmation via pathological examination, a retrospective analysis was performed on a cohort of 266 patients, comprising 115 individuals diagnosed with PNETs and 151 with pancreatic cancer. These patients were randomly assigned to the training or test group in a 7:3 ratio.
View Article and Find Full Text PDFAcad Radiol
January 2025
Department of Ultrasound, Chengdu Second People's Hospital, Chengdu 610000, China (X.L., X.Q.). Electronic address:
Rationale And Objectives: This study aims to develop a radiopathomics model based on preoperative ultrasound and fine-needle aspiration cytology (FNAC) images to enable accurate, non-invasive preoperative risk stratification for patients with papillary thyroid carcinoma (PTC). The model seeks to enhance clinical decision-making by optimizing preoperative treatment strategies.
Methods: A retrospective analysis was conducted on data from PTC patients who underwent thyroidectomy between October 2022 and May 2024 across six centers.
Int J Biol Macromol
January 2025
Nanotechnology Research Center, Faculty of Pharmacy, Tehran University of Medical Sciences, Tehran 1416634793, Iran; Wound Care Solution, Nano Fanavaran Narin Teb Co., Tehran, P.O. Box 19177-53531, Iran; Physical Chemistry I, Department of Chemistry and Biology & Research Center of Micro and Nanochemistry and Engineering (Cμ), University of Siegen, 57076 Siegen, Germany. Electronic address:
This study reports the development of a highly absorbent Chitosan (CS)/Tannic Acid (TA) sponge, synthesized via chemical cross-linking with Epichlorohydrin (ECH) and integrated with zinc oxide nanoparticles (ZnO NPs) as a novel hemostatic anti-infection agent. The chemical properties of the sponges were characterized using Fourier-transform infrared spectroscopy (FT-IR), X-ray diffraction (XRD), thermogravimetric analysis (TGA), and zeta potential measurements. Morphological and elemental analyses conducted through scanning electron microscopy (SEM) and energy-dispersive X-ray spectroscopy (EDAX) revealed a uniform distribution of ZnO NPs, with particle sizes below 20 nm.
View Article and Find Full Text PDFPLoS Pathog
January 2025
Department of Cancer and Genomic Sciences, College of Medicine and Health, University of Birmingham, Birmingham, United Kingdom.
Upon infection, human papillomavirus (HPV) manipulates host cell gene expression to create an environment that is supportive of a productive and persistent infection. The virus-induced changes to the host cell's transcriptome are thought to contribute to carcinogenesis. Here, we show by RNA-sequencing that oncogenic HPV18 episome replication in primary human foreskin keratinocytes (HFKs) drives host transcriptional changes that are consistent between multiple HFK donors.
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