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Single-Atom Catalysts Boosted Electrochemiluminescence.
Chempluschem
March 2025
Shanghai University, Chemistry, Shangda Road 99, 200444, Shanghai, CHINA.
Electrochemiluminescence (ECL) combines electrochemical redox processes with photochemical light emission, offering exceptional sensitivity, spatial control, and stability. Widely applied in biosensing, medical diagnostics, and environmental monitoring, its efficiency often depends on advanced catalytic materials. Single-atom catalysts (SACs), featuring isolated metal atoms dispersed on a support, have emerged as promising candidates due to their unique electronic structures, high atom utilization, and tunable catalytic properties.
View Article and Find Full Text PDFPoly(vinyl alcohol)/Polycaprolactone Nanofiber Enriched with Lichenysin against Multidrug-Resistance Bacterial Infection in Wound Healing: In Vitro Studies and In Vivo Evaluation in Wistar Rats.
ACS Appl Bio Mater
March 2025
Department of Pharmaceutical Sciences, Babasaheb Bhimrao Ambedkar University, Lucknow 226025, India.
Multidrug resistance (MDR) infectious wounds are a major concern due to drug resistance, leading to increased patient morbidity. Lichenysin (LCN), a lipopeptide and biosurfactant obtained from certain strains of , has demonstrated an excellent antimicrobial property. The present study focuses on the fabrication and comprehensive evaluation of LCN-incorporated poly(vinyl alcohol) (PVA)/polycaprolactone (PCL)-based nanofiber scaffolds using an electrospinning technique as a potential wound healing biomaterial for the treatment of MDR infectious wounds in diabetic rats.
View Article and Find Full Text PDFSpatial prediction of immunity gaps during a pandemic to inform decision making: A geostatistical case study of COVID-19 in Dominican Republic.
Trop Med Int Health
March 2025
UQ Centre for Clinical Research, Faculty of Medicine, The University of Queensland, Brisbane, Australia.
Background: To demonstrate the application and utility of geostatistical modelling to provide comprehensive high-resolution understanding of the population's protective immunity during a pandemic and identify pockets with sub-optimal protection.
Methods: Using data from a national cross-sectional household survey of 6620 individuals in the Dominican Republic (DR) from June to October 2021, we developed and applied geostatistical regression models to estimate and predict Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) spike (anti-S) antibodies (Ab) seroprevalence at high resolution (1 km) across heterogeneous areas.
Results: Spatial patterns in population immunity to SARS-CoV-2 varied across the DR.
Extracorporeal Membrane Oxygenation in the Treatment of Acute Elemental Mercury Inhalation Toxicity.
Chest
March 2025
Northwell Health Division of Medical Toxicology, North Shore University Hospital, Manhasset, NY.
Inhalation of elemental mercury is a rare cause of ARDS, with limited published case reports to provide guidance regarding disease progression and management. Although extracorporeal membrane oxygenation (ECMO) has been used to treat toxin-induced lung injury, its application to initial treatment and long-term recovery for inhalation of mercury remains undescribed. We present a case of a 56-year-old man who works at a thermometer factory presenting with severe ARDS secondary to inhaled elemental mercury with confirmatory blood and urine mercury levels.
View Article and Find Full Text PDFApplication of chemical pattern recognition and similarity evaluation in electrochemical and HPLC-DAD fingerprints for quality consistency study of herbal medicines.
Anal Chim Acta
May 2025
School of Pharmacy, Shenyang Pharmaceutical University, Shenyang, Liaoning, 110016, China. Electronic address:
Background: Herbal medicines and their preparations play a significant role in healthcare systems, yet concerns remain about their quality consistency. Chemical fingerprinting and multi-component quantitative analysis are the commonly used analytical methods and are widely applied in the quality analysis of herbal medicines. The study uses Gegen Qinlian tablets (GQTs) as a case to propose a comprehensive quality consistency evaluation system.
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