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1537-29956162021JunTransfusionTransfusionWould you like another pretzel? Water? We make progress in donor reactions.166516681665-166810.1111/trf.16442RossmannSusan NSNGulf Coast Regional Blood Center, Houston, Texas, United States.HartwellBeth ABAGulf Coast Regional Blood Center, Houston, Texas, United States.Department of Pathology & Immunology, Baylor College of Medicine, Houston, Texas, United States.engEditorial
United StatesTransfusion04173600041-1132IMBlood DonorsBlood TransfusionDrinkingHumansSyncope, Vasovagaletiologyprevention & controltherapy
2021532021532021618844202161960202172360ppublish3414272810.1111/trf.16442REFERENCESGoldman M, Uzicanin S, Marquis-Boyle L, O'Brien SF. Implementation of measures to reduce vasovagal reactions: donor participation and results. Transfusion. 2021. https://doi.org/10.1111/trf.16375.Newman BH, Newman DT, Ahmad R, Roth AJ. The effect of whole-blood donor adverse events on blood donor return rates. Transfusion. 2006;46:1374-9.Custer B, Rios JA, Schlumpf K, Kakaiya RM, Gottschall JL, Wright DJ; NHLBI Retrovirus Epidemiology Donor Study-II (REDS-II). Adverse reactions and other factors that impact subsequent blood donation visits. Transfusion. 2012;52:118-26.France CR, France JL, Himawan LK, Lux P, McCullough J. Donation related fears predict vasovagal reactions and donor attrition among high school donors. Transfusion. 2021;61:102-7.France CR, France JL, Frame-Brown TA, Venable GA, Menitove JE. Fear of blood draw and total draw time combine to predict vasovagal reactions among whole blood donors. Transfusion. 2016;56:179-85.Popovsky MA. Vasovagal donor reactions: an important issue with implications for the blood supply. Transfusion. 2002;42:1534-6.Newman BH. Vasovagal reactions in high school students: findings relative to race, risk factor synergism, female gender, and non-high school participants. Transfusion. 2002;42:1557-60.Tomita T, Takayanagi M, Kiwada K, Mieda A, Takahashi C, Hata T. Vasovagal reactions in apheresis donors. Transfusion. 2002;42:1561-6.Newman BH, Siegfried BA. The quest to reduce vasovagal reactions in young blood donors. Transfusion. 2011;51:2061-3.Trouern-Trend JJ, Cable RG, Badon SJ, Newman BH, Popovsky MA. A case-controlled multicenter study of vasovagal reactions in blood donors: influence of sex, age, donation status, weight, blood pressure, and pulse. Transfusion. 1999;39:316-20.Eder AF, Hillyer CD, Dy BA, Notari EP 4th, Benjamin RJ. Adverse reactions to allogeneic whole blood donation by 16- and 17-year-olds. JAMA. 2008;299:2279-86.Tomasulo P, Kamel H, Bravo M, James RC, Custer B. Interventions to reduce the vasovagal reaction rate in young whole blood donors. Transfusion. 2011;51:1511-21.Eder AF. Improving safety for young blood donors. Transfus Med Rev. 2012;26:14-26.Wieling W, France CR, van Dijk N, Kamel H, Thijs RD, Tomasulo P. Physiologic strategies to prevent fainting responses during or after whole blood donation. Transfusion. 2011;51:2727-38.Thijsen A, Masser B, Davison TE. Reduced risk of vasovagal reactions in Australian whole blood donors after national implementation of applied muscle tension and water loading. Transfusion. 2020;60:918-21.Thijsen A, Masser B. Vasovagal reactions in blood donors: risks, prevention and management. Transfus Med. 2019;29(Suppl 1):13-22.Thijsen A, Gemelli CN, Davison TE, O'Donovan J, Bell B, Masser B. Does using applied muscle tension at strategic time points during donation reduce phlebotomist- and donor-reported vasovagal reaction rates? A three-armed randomized controlled trial. Transfusion. 2018;58:2352-9.Morand C, Coudurier N, Rolland C, Thoret S, Legrand D, Tiberghien P, et al. Prevention of syncopal-type reactions after whole blood donation: a cluster-randomized trial assessing hydration and muscle tension exercise. Transfusion. 2016;56:2412-21.Mennitto S, Harrison J, Ritz T, Robillard P, France CR, Ditto B. Respiration and applied tension strategies to reduce vasovagal reactions to blood donation: a randomized controlled trial. Transfusion. 2019;59:566-73.Ditto B, France CR, Holly C. Applied tension may help retain donors who are ambivalent about needles. Vox Sang. 2010;98:e225-30.France CR, France JL, Kowalsky JM, Cornett TL. Education in donation coping strategies encourages individuals to give blood: further evaluation of a donor recruitment brochure. Transfusion. 2010;50:85-91.France CR, France JL, Carlson BW, Himawan LK, Stephens KY, Frame-Brown TA, et al. Fear of blood draws, vasovagal reactions, and retention among high school donors. Transfusion. 2014;54:918-24.France CR, France JL, Kowalsky JM, Ellis GD, Copley DM, Geneser A, et al. Assessment of donor fear enhances prediction of presyncopal symptoms among volunteer blood donors. Transfusion. 2012;52:375-80.Wiersum-Osselton JC, Marijt-van der Kreek T, Brand A, Veldhuizen I, van der Bom JG, de Kort W. Risk factors for complications in donors at first and repeat whole blood donation: a cohort study with assessment of the impact on donor return. Blood Transfus. 2014;12 (Suppl 1):s28-36.
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