Background: Chronic limb-threatening ischemia is a severe form of peripheral artery disease that leads to high rates of amputation and mortality if left untreated. Bypass surgery and antegrade endovascular revascularization through femoral artery access from either side are accepted as conventional treatment modalities for critical limb ischemia. The retrograde pedal access revascularization is an alternative treatment modality useful in specific clinical scenarios; however, these indications have not been well described in literature. This case report highlights the use of retrograde pedal access approach as primary treatment modality in a patient with an extensive comorbidities precluding general anesthesia nor supine positioning.
Case Presentation: The patient is a 60-year-old female with multiple severe cardiopulmonary comorbidities presenting with dry gangrene of the right great toe. Her comorbidities and inability to tolerate supine positioning precluded her from receiving open surgery, general anesthesia or monitored sedation, or percutaneous femoral access. Rather, the patient underwent ankle block and retrograde endovascular revascularization via dorsalis pedis artery access without post-operative complications.
Discussion: The prevalence of comorbidities related to peripheral artery disease is increasing and with it the number of patients who are not optimal candidates for conventional treatment methods for critical limb ischemia. The retrograde pedal access revascularization as initial treatment modality offers these patients an alternative limb salvaging treatment option.
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http://dx.doi.org/10.1177/15385744211026451 | DOI Listing |
Sci Rep
January 2025
Department of Sport & Health, Exercise Science & Neuroscience Unit Universität Paderborn, Warburger Straße 100, 33098, Paderborn, Germany.
Anterior cruciate ligament injuries (ACLi) impact football players substantially leading to performance declines and premature career endings. Emerging evidence suggests that ACLi should be viewed not merely as peripheral injuries but as complex conditions with neurophysiological aspects. The objective of the present study was to compare kicking performance and associated cortical activity between injured and healthy players.
View Article and Find Full Text PDFIndian J Plast Surg
December 2024
University of Medicine and Pharmacy at Ho Chi Minh City, Ho Chi Minh City, Vietnam.
Treatment of soft-tissue defects in the foot and ankle is a challenge. The use of a retrograde lateral supramalleolar flap is a promising technique for reconstruction. This study aims to assess the efficacy and outcomes of the technique.
View Article and Find Full Text PDFBrain Res Bull
January 2025
Psychophysiology Laboratory, Wannan Medical College, Wuhu, Anhui 241002, China. Electronic address:
Post-traumatic stress disorder (PTSD) is characterized by anxiety, excessive fear, distress, and weakness as symptoms of a psychiatric disorder. However, the mechanism associated with its symptoms such as anxiety-like behaviors is not well understood. It is aimed to investigate the underlying mechanisms of the medial septum (MS)-medial habenula (MHb) neural circuit modulating the anxiety-like behaviors of PTSD mice through in vivo fiber photometry recording, optogenetics, behavioral testing by open-field and elevated plus maze, fluorescent gold retrograde tracer technology, and viral tracer technology.
View Article and Find Full Text PDFAnn Plast Surg
February 2025
From the Department of Hand and Foot Surgery, The Second Affiliated Hospital of Soochow University, Suzhou, China.
Background: Complex lower extremity defects are difficult to cover and often require multiple free tissue transfers. Chimeric anterolateral thigh free flaps (ALTF) and peroneal artery perforator free flaps (PAPF) have been designed specifically as an alternative for reconstruction with arterial end-to-side (ETS) anastomosis. We aimed to assess our institutional experience with this technique and to define its role in complex lower extremity reconstruction.
View Article and Find Full Text PDFKhirurgiia (Mosk)
December 2024
Petrozavodsk State University, Petrozavodsk, Russia.
Objective: To evaluate the mid-term results of endovascular revascularization of the lower extremities through primary retrograde distal approach.
Material And Methods: We prospectively analyzed the mid-term results of 74 endovascular surgeries via primary retrograde distal approach in 69 patients with lower extremity ischemia. Mean age of patients was 68.
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