AI Article Synopsis
- The IFIT family, comprising IFIT1, IFIT2, IFIT3, and IFIT5, plays a crucial role in the antiviral immune response in humans.
- Recent research indicates that these proteins also have significant implications in cancer biology.
- This review discusses the functions of IFIT proteins in different cancers and explores their potential as biomarkers and prognostic indicators.
Article Abstract
The Interferon-induced protein with tetratricopeptide repeats (IFIT) family is an important component of the antiviral immune response. There are currently four known IFIT family members in humans, namely IFIT1, IFIT2, IFIT3 and IFIT5. Recent discoveries have brought attention to the significant roles of IFITs in cancer. This review summarises current knowledge on the biological roles of different IFIT proteins in various types of malignant neoplasm, and highlights the potential use of these molecules as cancer biomarkers and prognostic factors.
Download full-text PDF |
Source |
|---|---|
| http://dx.doi.org/10.2174/0929867328666210617105209 | DOI Listing |
Publication Analysis
Top Keywords
ifit family
12
protein tetratricopeptide
8
tetratricopeptide repeats
8
repeats ifit
8
roles interferon
4
interferon induced
4
induced protein
4
ifit
4
family cancer
4
cancer interferon-induced
4
Similar Publications
Want AI Summaries of new PubMed Abstracts delivered to your In-box?
Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!