Systematic review: Exploration of the impact of psychosocial factors on quality of life in adults living with coeliac disease.

J Psychosom Res

Department of Psychological Sciences, Faculty of Health, Arts and Design, Swinburne University of Technology, Hawthorn, VIC, Australia; Department of Gastroenterology, Alfred Health, Prahran, VIC, Australia. Electronic address:

Published: August 2021

AI Article Synopsis

  • Individuals with coeliac disease often see improvements in symptoms after starting a gluten-free diet, but many still struggle with quality of life and treatment challenges.
  • A review of 14 studies with over 3,300 participants (mostly women) found that factors like depression, anxiety, and attitudes towards food impacted their quality of life.
  • The study highlights the need for more research on how these psychosocial factors interconnect and affect well-being, aiming to find ways to support better mental health and diet adherence among those with coeliac disease.

Article Abstract

Background: Individuals living with coeliac disease generally experience a remission of symptoms after adopting the gluten-free diet but often report substantial treatment burden and ongoing quality of life issues. Psychosocial factors have been suggested to play a significant role in post-diagnosis quality of life but have yet to be systematically reviewed.

Aim: To review the evidence for psychosocial factors associated with quality of life in adult coeliac disease cohorts.

Methods: Studies were identified via systematic searches of eight databases (MEDLINE, Embase, Emcare, PsycINFO, Ovid Nursing, CINAHL, Informit Health Collection, Cochrane Library) in May 2019.

Results: Fourteen studies were included involving 3372 participants (80.2% female, mean age = 46.4 years). Symptoms of depression and anxiety were the most examined psychosocial factors across all studies. Quality of life was differentially associated with psychological distress, illness perceptions, coping, and attitudes/behaviours regarding food and the gluten-free diet.

Conclusion: Several psychosocial factors are associated with quality of life in adults living with coeliac disease. Current evidence suggests these factors are interrelated and may influence quality of life directly, via reduced psychological well-being, and indirectly, via reduced adherence to the gluten-free diet. Future research is needed to examine these processes concurrently, with the aim of elucidating the psychosocial mechanisms underlying post-diagnosis well-being and identifying potential targets for psychosocial intervention.

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Source
http://dx.doi.org/10.1016/j.jpsychores.2021.110537DOI Listing

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