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http://dx.doi.org/10.1371/journal.pntd.0009437DOI Listing

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Background: Noma is a rapidly progressing, invasive, and debilitating orofacial disease that primarily affects the most vulnerable and marginalised populations worldwide. The highest- risk group includes pre-school children, exposed to other risk factors, such as malnutrition and poverty-related diseases. Since 2010, Ethiopia has reported an increasing number of noma cases, primarily identified through medical missions.

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Noma, or Cancrum oris, is a severe and rapidly progressing gangrenous infection that primarily affects the face. It is most commonly observed in children living in impoverished conditions, especially in sub-Saharan Africa. Rapid diagnosis and early management are crucial to prevent devastating consequences, such as functional limitations and serious psychological repercussions.

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Background: Recently recognized by the World Health Organization as a neglected tropical disease, Noma, an acute and destructive gangrenous disease affecting the gums and facial structures within the oral cavity, has a high mortality rate if untreated.

Objectives: To investigate the prevalence and impact of Noma among internally displaced populations in Northeastern Nigeria.

Design: A retrospective study.

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Article Synopsis
  • * Risk factors for Noma include malnutrition, poor dental hygiene, low socioeconomic status, and certain health conditions, with mortality rates around 8.5% in Niger.
  • * Management includes antibiotics, surgical treatment, and wound care, while prevention focuses on improving oral hygiene, education, and community interventions. The WHO's recognition of Noma underscores the need for early intervention and prevention strategies to improve health outcomes globally.
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Noma finally recognised as a neglected tropical disease.

PLoS Negl Trop Dis

May 2024

Department of Infection Biology and Microbiomes, Institute of Infection, Veterinary and Ecological Sciences, University of Liverpool, Liverpool, United Kingdom.

In December 2023, after decades of tireless advocacy from stakeholders and partners, the World Health Organization (WHO) gave noma the long overdue recognition as a neglected tropical disease. The significance of this official recognition cannot be overstated, and it is hoped this will serve as a turning point in our battle against this devastating disease.

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