Single administration of monohydric alcohols to rats in equitoxic doses corresponding to 1/5 LD50 results in a cytogenetic effect which depends on a chemical structure of the alcohol molecule. The isomers are less active chemicals than the normal counterparts.
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Analysis of the effect of permeant solutes on the hydraulic resistance of the plasma membrane in cells of Chara corallina.
Protoplasma
October 2024
Institute of Plant Science and Resources (IPSR), Okayama University, 2-20-1, Chuo, Kurashiki, 710-0046, Japan.
In the cells of Chara corallina, permeant monohydric alcohols including methanol, ethanol and 1-propanol increased the hydraulic resistance of the membrane (Lp). We found that the relative value of the hydraulic resistance (Lp) was linearly dependent on the concentration (C) of the alcohol. The relationship is expressed in the equation: Lp = ρC + 1, where ρ is the hydraulic resistance modifier coefficient of the membrane.
View Article and Find Full Text PDFIn the process of polysaccharide gel formation: A review of the role of competitive relationship between water and alcohol molecules.
Int J Biol Macromol
November 2024
Department of Chemical Engineering, University of Bath, Bath BA2 7AY, United Kingdom. Electronic address:
Polysaccharides have emerged as versatile materials capable of forming gels through diverse induction methods, with alcohol-induced polysaccharide gels demonstrating significant potential across food, medicinal, and other domains. The existing research mainly focused on the phenomena and mechanisms of alcohol-induced gel formation in specific polysaccharides. Therefore, this review provides a comprehensive overview of the intricate mechanisms underpinning alcohol-triggered gelation of different polysaccharides and surveys their prominent application potentials through rheological, mechanical, and other characterizations.
View Article and Find Full Text PDFHydrogen bond network structures of protonated dimethylamine clusters H(DMA) ( = 3-7).
Phys Chem Chem Phys
July 2024
Department of Chemistry, Graduate School of Science, Tohoku University, Sendai 980-8578, Japan.
Infrared spectroscopy of protonated dimethylamine clusters, H(DMA), ( = 3-7), and their Ar-tagged clusters was performed in the NH and CH stretching vibrational region to explore their hydrogen bond network structures. A stable isomer search and vibrational spectral simulations of the clusters were also carried out to support the interpretations of the observed spectra. Weakly hydrogen-bonded NH stretching vibrational bands, which are characteristic of cyclic structures of small-sized protonated clusters, are observed in the spectra of the Ar-tagged clusters of ≥ 5, while only linear chain type structures are suggested for the Ar-tagged clusters of = 3-4 and the bare clusters of all the sizes.
View Article and Find Full Text PDFModeling order-disorder boundaries of colloidal dispersions in organic solvents using interaction force measurements.
J Colloid Interface Sci
August 2024
Department of Chemical Engineering, Kyoto University, Katsura, Nishikyo, Kyoto 615-8510, Japan. Electronic address:
Hypothesis: The formation of soft colloidal crystals, which are nonclose-packed ordered arrays of colloidal particles suspended in a solvent, is dictated by a single physical factor that yields a fixed threshold at order-disorder boundaries for different experimental conditions such as ion concentration, solvent type, and particle size. Identifying the determinant factor and its threshold value should enable the prediction of the critical concentrations of colloidal particles to form soft colloidal crystals.
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Molecular mechanism of the common and opposing cosolvent effects of fluorinated alcohol and urea on a coiled coil protein.
Protein Sci
October 2023
Department of Bio-Science, Nagahama Institute of Bio-Science and Technology, Nagahama, Shiga, Japan.
Alcohols and urea are widely used as effective protein denaturants. Among monohydric alcohols, 2,2,2-trifluoroethanol (TFE) has large cosolvent effects as a helix stabilizer in proteins. In contrast, urea efficiently denatures ordered native structures, including helices, into coils.
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