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Evaluation of dietary supplementation of omega-3 polyunsaturated fatty acids as an adjunct to scaling and root planing on salivary interleukin-1β levels in patients with chronic periodontitis: A clinico-immunological study.
J Indian Soc Periodontol
January 2017
Department of Microbiology, JSS Medical College and Hospital, Jagadguru Sri Shivarathreeshwara University, Mysore, Karnataka, India.
Context: Host modulation with omega-3 polyunsaturated fatty acids (ω-3 PUFAs) has anti-inflammatory and pro-resolution actions through replacing and inhibiting metabolism of arachidonic acid (AA).
Aim: This study was aimed at evaluating clinical parameters and salivary levels of interleukin-1 beta (IL-1β) after scaling and root planing (SRP) in chronic periodontitis patients, with and without dietary supplementation of ω-3 PUFAs.
Settings And Design: Forty otherwise healthy participants with severe chronic periodontitis were included.
HMGB1/RAGE Signaling and Pro-Inflammatory Cytokine Responses in Non-HIV Adults with Active Pulmonary Tuberculosis.
PLoS One
July 2017
Department of Medicine and Therapeutics, Prince of Wales Hospital, Hong Kong SAR, China.
Background: We aimed to study the pathogenic roles of High-Mobility Group Box 1 (HMGB1) / Receptor-for-Advanced-Glycation-End-products (RAGE) signaling and pro-inflammatory cytokines in patients with active pulmonary tuberculosis (PTB).
Methods: A prospective study was conducted among non-HIV adults newly-diagnosed with active PTB at two acute-care hospitals (n = 80); age-and-sex matched asymptomatic individuals (tested for latent TB) were used for comparison (n = 45). Plasma concentrations of 8 cytokines/chemokines, HMGB1, soluble-RAGE, and transmembrane-RAGE expressed on monocytes/dendritic cells, were measured.
Clinico-immunological profile and their correlation with severity of atopic dermatitis in Eastern Indian children.
J Nat Sci Biol Med
January 2014
Department of Pathology, Narayan Medical College and Hospital, Jamuhar, Sasaram, Bihar, India.
Objective: To study the clinical features, absolute eosinophil count, and total immunoglobulin E (IgE) level and their association with severity of atopic dermatitis in Eastern Indian children (Bihar).
Design: Prospective hospital-based study.
Settings: Pediatrics out-patient Department (OPD) and Dermatology OPD of a Tertiary Care Teaching Hospital located in Rohtas District of Bihar.
Papular pruritic eruptions: A marker of progressive HIV disease in children: Experience from eastern India.
Indian J Sex Transm Dis AIDS
July 2009
Department of Pediatric Medicine, Medical College and Hospital, Kolkata, India.
Context: Papular pruritic eruptions (PPEs) are a commonly seen dermatological manifestation in children with Human Immunodeficiency Virus (HIV) stage 2 disease, whereas recurrent upper respiratory tract infection (URTI) (<2 episodes in 6 months) is the most common presenting illness in this category. Papular pruritic eruptions has been associated with progressive HIV disease in adults though it is categorized in early stage.
Aim: To evaluate PPE as a clinical marker for progressive pediatric HIV.
[Clinico-immunological comparisons in evaluation of interferon system functioning in patients with multiple sclerosis].
Zh Nevrol Psikhiatr Im S S Korsakova
March 2003
In search for rational approach for immunotherapy individualization in patients with multiple sclerosis (MS) assigned to interferon (IFN) treatment, an evaluation of IFN-alpha and IFN-gamma production by peripheral blood leucocytes (PBL) under standard induction and exogenous IFN priming in comparison with clinical characteristics was made. Fifteen patients with MS (6 males and 9 females, aged 25-58 years) with verified diagnosis of MS were examined. IFN production priming allowed to obtain characteristics of IFN system deficiency, which could not be detected by standard induction methods.
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