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Low-Dose Initiations of Buprenorphine in the Fentanyl Era-A Search for Evidence-Based Approaches to an Evolving Crisis.
JAMA Netw Open
January 2025
Department of Medicine, University of Pennsylvania Perelman School of Medicine, Philadelphia.
Nephrectomy in Autosomal Dominant Polycystic Kidney Disease: A consensus statement of the ERA Genes & Kidney Working Group.
Nephrol Dial Transplant
January 2025
Department of Urology, University Medical Center Groningen, University of Groningen, Groningen, The Netherlands.
A substantial number of patients with Autosomal Dominant Polycystic Kidney Disease (ADPKD) undergo a nephrectomy, especially in work-up for a kidney transplantation. Currently, there is no evidence-based algorithm to guide clinicians which patients should undergo nephrectomy, the optimal timing of this procedure, or the preferred surgical technique. This systematic review-based consensus statement aimed to answer important questions regarding nephrectomy in ADPKD.
View Article and Find Full Text PDFSocial connectedness, defined as a sense of belonging and inclusion among individuals and groups, is crucial for the well-being of end-stage kidney disease (ESKD) patients. This perspective employs a hypothetical case study to highlight the risks of social isolation and loneliness faced by ESKD patients. It offers guidance on how the ESKD community can effectively address these challenges.
View Article and Find Full Text PDFExpert consensus and recommendations on the live attenuated hepatitis A vaccine and immunization practices in India.
Hum Vaccin Immunother
December 2025
Department of Paediatrics, Institute of Child Health, Kolkata, India.
While Hepatitis A Virus (HAV) vaccination in global immunization programs has shown a virtual elimination of the disease within few years of the vaccination program, changing epidemiological landscape in India underscores the need for evidence-based, updated guidance on immunization practices. In May 2024, a panel of 15 distinguished opinion leaders and an organizing committee convened for an intensive, face-to-face advisory board meeting on high burden of HAV infection among adults, increased mortality rate in adolescents, symptomatic presentation in children, and evolving landscape globally and within India. Extensive comparable deliberations on long-term follow-up data from India and data from country of origin advocated immunogenicity, tolerability, and long-term protective effects of single-dose live attenuated HAV vaccine in children.
View Article and Find Full Text PDFPsychological Interventions to Improve Elite Athlete Mental Wellbeing: A Systematic Review and Meta-analysis.
Sports Med
January 2025
School of Psychology, University of Wollongong, Wollongong, NSW, 2500, Australia.
Background: Mental wellbeing, one continuum alongside mental illness in a dual-continua mental health model, has attracted less attention compared with substantial studies concerning mental illness amongst elite athletes. Notably, the promotion and protection of mental wellbeing contribute to not only a positive status of flourishing but also a reduction in the future risk of mental illness, which can potentially facilitate a status of complete mental health. Despite the critical role of wellbeing promotion and protection, there are limited evidence-based strategies to design and implement wellbeing interventions in elite athletes.
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