AI Article Synopsis
- The study investigated the expression of surfactant proteins A and D (SP-A and SP-D) in the uterine and placental tissues of 13 pregnant mares using specific antibodies.
- Strong positive reactions for both proteins were found in the placenta's trophoblasts during the later stages of gestation, while weaker reactions were noted in the uterine epithelial cells.
- This research is the first to document changes in SP-A and SP-D expression levels in mare endometrium throughout pregnancy, with increased levels observed after the second trimester.
Article Abstract
Immunohistochemical investigations of the expression of surfactant protein A (SP-A) and surfactant protein D (SP-D) in the uterine and placental tissues of 13 pregnant mares were performed using anti-horse monoclonal primary antibodies. Strong positive reactions for both SP-A and SP-D were observed in the trophoblasts in the microcotyledons of the placentae at 182 to 314 days of gestation; in uterine glandular epithelial cells, faint-to-weak reactions were observed during gestation. This study describes, for the first time, the changes in the SP-A and SP-D expression levels in the endometrium of mares during gestation; the SP-A and SP-D expression levels increased after the second trimester of gestation.
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| http://www.ncbi.nlm.nih.gov/pmc/articles/PMC8349814 | PMC |
| http://dx.doi.org/10.1292/jvms.20-0174 | DOI Listing |
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