AI Article Synopsis
- - A 14-year-old patient at UCLA Medical Center presented with fever, weight loss, and low blood cell counts, leading to the diagnosis of Kikuchi-Fujimoto disease (KFD).
- - Physical examination revealed painful subcutaneous nodules and swollen lymph nodes, which were confirmed as KFD through a lymph node biopsy.
- - A skin biopsy showed unusual findings, including mild swelling and inflammation, along with rare atypical cells, suggesting a connection between KFD and Sweet syndrome, although such a relationship hasn't been documented before.
Article Abstract
We present a case of the rare Kikuchi-Fujimoto disease (KFD) in a 14-year-old patient admitted to UCLA Medical Center with fever, weight loss, and pancytopenia. Physical examination revealed tender subcutaneous nodules and cervical lymphadenopathy. A lymph node biopsy showed findings consistent with KFD. The skin biopsy showed mild superficial dermal edema with neutrophil-predominant inflammation. In addition, rare atypical monocytoid cells were seen. This histologic finding of a Sweet-like morphology has not been reported previously in the literature in association with KFD. The differential diagnosis included Sweet syndrome arising in association with KFD, underlying connective tissue, and an infectious etiology.
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| http://dx.doi.org/10.1097/DAD.0000000000001965 | DOI Listing |
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