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A general procedure for carbon isotope labeling of linear urea derivatives with carbon dioxide. | LitMetric

AI Article Synopsis

  • Carbon isotope labeling is a method used to track organic compounds in both environmental and biological contexts without leaving a trace.
  • The article discusses a new technique to label urea derivatives with various carbon isotopes, such as 14C and 11C, utilizing a process called the Staudinger aza-Wittig sequence.
  • This approach enables the creation of a wide range of urea combinations, both aliphatic and aromatic.

Article Abstract

Carbon isotope labeling is a traceless technology, which allows tracking the fate of organic compounds either in the environment or in living organisms. This article reports on a general approach to label urea derivatives with all carbon isotopes, including 14C and 11C, based on a Staudinger aza-Wittig sequence. It provides access to all aliphatic/aromatic urea combinations.

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Source
http://dx.doi.org/10.1039/d1cc02665hDOI Listing

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