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Does the power of the laser devices matter for a successful HoLEP procedure? A prospective comparative study. | LitMetric

AI Article Synopsis

  • - The study aimed to compare the efficiency, safety, and applicability of medium-power (MP) vs. high-power (HP) holmium laser devices for endoscopic enucleation of an enlarged prostate (HoLEP) using 120 patients divided into two groups. - Results showed no significant differences in patient characteristics, enucleation efficiency, haemoglobin decrease, catheterization time, or hospital stay between the MP and HP groups; both groups experienced similar improvements in functional outcomes after 3 months. - The study concluded that HoLEP can be safely and effectively performed with MP laser devices without facing technical difficulties, making them a viable alternative to HP lasers in this surgical procedure.

Article Abstract

Background: The objectives of this prospective study were to evaluate the efficiency, safety and applicability of medium-power (MP) holmium laser devices in the endoscopic enucleation of the enlarged prostate (HoLEP) compared with high-power (HP) laser devices.

Methods: From October 2019 to July 2020, a total of 120 consecutive patients planned for HoLEP were divided randomly into two groups formed in terms of the power of the device used. While patients in group 1 were treated with a MP device (50 W) at 39.6 W (2.2 J/18 Hz), patients in group 2 were treated with HP (100 W) device at 42 W (1.2 J/35 Hz). Preoperative patient characteristics, perioperative measures and 3-month functional outcomes were evaluated in both groups with an emphasis on enucleation efficiency (EE) and haemoglobin decrease in a comparative manner.

Results: All patients underwent successful HoLEP surgery with no severe perioperative and postoperative complications. No statistically significant differences were observed in terms of preoperative patient characteristics and perioperative measures in the two groups. The median EE values in groups 1 and 2 were 1.15 (interquartile range [IQR]: 0.33-2.2) and 1.11 (IQR: 0.4-2.8), respectively (P = .775). Haemoglobin decrease values in groups 1 and 2 were 1.3 (IQR: 0.1-4) and 1.4 (IQR: 0.4-3.1), respectively (P = .736). There was no difference in terms of either catheterisation time or hospital stay in the groups. In the model created to predict haemoglobin decrease, only biopsy was detected to be the independent predictive factor among the data from laser device, biopsy and antithrombotic use. Functional outcomes markedly improved in all patients without any statistically significant difference between the groups in the 3-month follow-up.

Conclusion: Our comparative study indicated that HoLEP can be performed safely and effectively with MP laser devices without any technical difficulties and with comparable results achieved in HP laser devices.

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Source
http://dx.doi.org/10.1111/ijcp.14531DOI Listing

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