A crystalline-fiber-based Mirau-type full-field optical coherence tomography (FF-OCT) system utilizing two partially coherent illumination modes is presented. Using a diode-pumped Ti:sapphire crystalline fiber with a high numerical aperture, spatially-incoherent broadband emission can be generated with high radiance. With two modes of different spatial coherence settings, either deeper penetration depth or higher B-scan rate can be achieved. In a wide-field illumination mode, the system functions like FF-OCT with partially coherent illumination to improve the penetration depth. In a strip-field illumination mode, a compressed field is generated on the sample, and a low-speckle B-scan can be acquired by compounding pixel lines within.
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http://dx.doi.org/10.1364/BOE.422622 | DOI Listing |
Anal Chem
January 2025
State Key Laboratory of Supramolecular Structure and Materials, College of Chemistry, Jilin University, Changchun 130012, China.
As the most common and lethal cancer of the female gonads, ovarian cancer (OC) has a grave impact on people's health. OC is asymptomatic, insidious in onset, difficult to diagnose and treat, fast-growing, and easy to metastasize and has poor prognosis and high mortality. How to detect OC as early as possible and treat it without side effects has become a challenging medical problem.
View Article and Find Full Text PDFCardiovasc Eng Technol
January 2025
Department of Research and Development, Nonprofit Organization of Research Institute of Life Benefit, Sapporo, Hokkaido, 005-0006, Japan.
Purpose: Dysfunction of vasomotor reactions due to arteriolar smooth muscle causes serious adverse events, such as loss of hemodynamic coherence. This in turn can increase risks of cardiovascular-related diseases. A noninvasive and quantitative evaluation of microvascular disorder is therefore very important for early diagnosis and treatment.
View Article and Find Full Text PDFNPJ Digit Med
January 2025
School of Mechanical Engineering, Shandong University, Jinan, China.
Extensive research on retinal layer segmentation (RLS) using deep learning (DL) is mostly approaching a performance plateau, primarily due to reliance on structural information alone. To address the present situation, we conduct the first study on the impact of multi-spectral information (MSI) on RLS. Our experimental results show that incorporating MSI significantly improves segmentation accuracy for retinal layer optical coherence tomography (OCT) images.
View Article and Find Full Text PDFACS Nano
January 2025
State Key Laboratory of Pollution Control and Resources Reuse, College of Environmental Science and Engineering, Tongji University, Shanghai 200092, China.
Photothermal disinfection (PTD) offers promising potential for water purification due to its sustainable and broad-spectrum bactericidal properties, although it is hindered by slow charge separation in photosensitizers. Herein, we present a plasma-mediated PTD technique utilizing an efficient localized heating effect induced by incident light at specific wavelengths for rapid bacterial inactivation. A metallic CuS photosensitizer, derived from electronic waste through a biomimetic transmembrane confined-assembled strategy, facilitates collective and coherent oscillation of free electrons around Cu atoms in the near-infrared range.
View Article and Find Full Text PDFEye (Lond)
January 2025
Save Sight Institute, Faculty of Medicine and Health, The University of Sydney, Sydney, NSW, Australia.
Purpose: To determine how Hardy-Rand-Rittler (HRR) colour vision testing correlates with visual functional and structural assessments in Cone and Cone-Rod Dystrophy.
Methods: Thirty-four Cone and 69 Cone-Rod Dystrophy patients diagnosed by electroretinography (ERG) at the Save Sight Institute in Sydney were included in a retrospective analysis. Each patient's HRR colour vision test scores were compared with markers of cone and rod system function including visual acuity (VA), ERG responses, changes on Spectral Domain Optical Coherence Tomography (OCT) and Fundus Autofluorescence.
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