[This corrects the article DOI: 10.1039/C9SC03914G.].
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http://dx.doi.org/10.1039/c9sc90268f | DOI Listing |
J Org Chem
January 2025
Department of Radiology, Mayo Clinic, Rochester, Minnesota 55906, United States.
Conjugation of radiofluorinated prosthetic groups to primary amines of peptides in an aqueous medium is still considerably challenging. Herein, we report a one-pot cascade synthesis of 1-[F]fluoro-4-isothiocyanatobenzene ([F]), an isothiocyanate-functionalized prosthetic group for radiolabeling of various peptides in aqueous medium. The developed compound [F] was synthesized in >99% radiochemical purity with 22.
View Article and Find Full Text PDFSci Rep
November 2024
Department of Chemistry and NIS Centre, University of Torino, Via Giuria 7, 10125, Torino, Italy.
RSC Adv
October 2024
Department of Organic Chemistry, Faculty of Chemistry, Bu-Ali Sina University Hamedan 6517838683 Iran +98 81 38380647.
[This corrects the article DOI: 10.1039/D2RA05070F.].
View Article and Find Full Text PDFMethods Mol Biol
October 2024
European Molecular Biology Laboratory (EMBL), Genome Biology Unit, Heidelberg, Germany.
Both regulatory sequences and genome organization contribute to the production of diverse transcript isoforms, which can influence how genes, or sets of genes, are expressed. An efficient, modular approach is needed to generate the combinatorial complexity required to empirically test many combinations of different regulatory sequences and different gene orders. Golden Gate assembly provides such a tool for seamless one-pot cleavage and ligation, by using type IIS restriction enzymes, which cleave outside of their recognition site.
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