The Chrysopogon zizanioides plant possesses multiple traditional uses, especially in therapeutics, but only a few articles have reported its biological activity. Hence, the present study was planned to explore the phytochemical constituents, cytotoxic potential, radical scavenging activity, and GC/MS (Gas chromatography & Mass spectrometry) analysis of the vetiver root extracts. The roots extracted with different solvents exhibited more significant phytochemical constituents in polar solvents in comparison to non-polar ones, favoring the extraction of a greater number of components in highly polar solvents. All the extracts were tested for their cytotoxicity using SRB (Sulforhodamine B) assay. They confirmed ethanolic extract as a potent extract with GI 56±0.5 μg/ml in oral cancer (SCC-29B) along with no cytotoxicity in healthy cells (Vero cells), making it a safer therapeutic option in comparison to standard Adriamycin. This extract was also analyzed for its antioxidant potential by DPPH (1,1-Diphenyl-2-picrylhydrazyl) assay with IC value 10.73 μg/ml, which was quite comparable to Ascorbic acid having IC value 4.61 μg/ml. The quantitative analysis of ethanolic extract exhibited 107 compounds amongst which Khusenic acid, Ascorbic acid, Junipen, gamma-Himachalene, alpha-Guaiene were the majorly occurring compounds that can be explored further for their cytotoxic activity.
Download full-text PDF |
Source |
|---|---|
| http://dx.doi.org/10.1002/cbdv.202100012 | DOI Listing |
Publication Analysis
Top Keywords
Similar Publications
Myco-assisted phytoextraction of heavy metals with vetiver grass: a green technology for cleaning tannery effluent contaminated sites.
Environ Monit Assess
November 2024
Nammazhvar Organic Farming Research Centre, Tamil Nadu Agricultural University, Coimbatore, 641003, Tamil Nadu, India.
Article Synopsis
- Metal toxicity impacts plant physiology, and mycorrhizal fungi (AMF) offer a new eco-friendly method to improve soil contaminated by tannery effluents, which are high in harmful metals like chromium and cadmium.* -
- A study was conducted using vetiver grass and three strains of AMF on contaminated soil from Tamil Nadu, revealing that AMF inoculation, particularly with R. intraradices, boosted plant growth and biomass significantly compared to other treatments.* -
- Results indicated that R. intraradices improved the phytoextraction of metals, reduced their movement into plant shoots, and increased carbon storage in vetiver, enhancing overall carbon sequestration in contaminated soil.*
Vetiveria zizanioides modulates experimental epilepsy-induced seizures, oxidative stress, and apoptosis in the brain of rats.
Metab Brain Dis
November 2024
Department of Physiology, Faculty of Medicine, Süleyman Demirel University, Isparta, 32260, Turkey.
Article Synopsis
- The study explored the effects of Vetiveria zizanioides oil (VET) on oxidative stress and cell death in rats that experienced seizures induced by pentylenetetrazol (PTZ).
- Four groups of rats were observed: a control group, a PTZ only group, and two groups receiving different doses of VET alongside the PTZ treatment.
- Findings indicated that PTZ increased seizure activity and caused oxidative stress, but treatment with VET significantly reduced these negative effects and improved the overall condition of the rats' brain tissues.
The role of plant uptake in total phosphorous and total nitrogen removal in vegetated bioretention cells using vetiver and cattail.
Chemosphere
September 2024
State Key Joint Laboratory of Environmental Simulation and Pollution Control, School of Environment, Tsinghua University, Beijing, 100084, China; Institute of Environment and Ecology, Tsinghua Shenzhen International Graduate School, Shenzhen, 518055, China. Electronic address:
Bioretention cells have emerged as a prominent strategy for mitigating pollutant loads within urban stormwater runoff. This study delves into the role of plant uptake in the simultaneous removal of nitrogen and phosphorus compounds within these systems. Three bioretention cells-CP, P1, and P2-were constructed using local soil, C33 sand, and gravel.
View Article and Find Full Text PDFInfluence of biochar amendment on removal of heavy metal from soils using phytoremediation by Catharanthus roseus L. and Chrysopogon zizanioides L.
Environ Sci Pollut Res Int
August 2024
Department of Civil Engineering, Indian Institute of Technology, Guwahati, 781039, India.
Advances in sustainable toxic heavy metal treatment technologies are crucial to meet our needs for safer land to develop an urban resilient future. The heavy metals bioaccumulate in the food chain due to their persistence in the soil, which poses a serious challenge to its removal and control. Utilisation of hyperaccumulators to reduce the mobility, accumulation and toxic impact of heavy metals is a promising and ecologically safe technique.
View Article and Find Full Text PDFComparative evaluation of biodegradation of chlorpyrifos by various bacterial strains: Kinetics and pathway elucidation.
Pestic Biochem Physiol
August 2024
Crop Production and Protection Division, CSIR-Central Institute of Medicinal and Aromatic Plants, Lucknow 226015, India; Academy of Scientific and Innovative Research (AcSIR), Ghaziabad 201002, India. Electronic address:
The present study focused on the isolation and identification of CP and TCP bacteria degrading bacteria from the rhizospheric zone of aromatic grasses i.e. palmarosa (Cymbopogon martinii (Roxb.
View Article and Find Full Text PDFWant AI Summaries of new PubMed Abstracts delivered to your In-box?
Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!