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| http://dx.doi.org/10.1016/j.vaccine.2021.05.095 | DOI Listing |
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BackgroundClimate change is a huge public health threat, necessitating reductions in carbon emissions, particularly from single-use plastics like non-sterile gloves (NSG). This quality improvement project aims to explore whether use of targeted educational material changes staff attitudes towards NSG use in clinical practice within a Sexual Health and HIV department.MethodsA pre-intervention survey was circulated to all clinicians.
View Article and Find Full Text PDF" … They cannot help you because you're at McDonald's and you're asking for pizza". A qualitative exploration of the acceptability and appropriateness of integrating of pharmacotherapy for mental health treatment in HIV care among patients living with HIV and co-morbid mental health and substance use disorders.
AIDS Care
March 2025
SisterLove, Inc., Atlanta, GA, United States.
Mental health disorders contribute to a lack of HIV care retention and adherence. Pharmacotherapy for mental health treatment may increase retention and adherence. However, there is often a lack of pharmacotherapy services for mental health treatment available in HIV care.
View Article and Find Full Text PDFManagement of diarrhoea in patients with stable ulcerative colitis with low FODMAP diet, amitriptyline, ondansetron or loperamide: the MODULATE RCT.
Health Technol Assess
March 2025
Clinical Trials Research Unit, University of Leeds, Leeds, UK.
Background: Many patients with ulcerative colitis report ongoing diarrhoea even when their disease is stable and in remission.
Design: MODULATE was a pragmatic, multicentre, seamless, adaptive, phase 2/3 open-label, parallel-group, multiarm multistage randomised controlled trial.
Setting And Participants: People aged over 18 years with stable ulcerative colitis who had diarrhoea, recruited from secondary care sites in the United Kingdom.
Ethical and legal considerations in normothermic regional perfusion for donation after circulatory death.
Curr Opin Crit Care
March 2025
Baylor Scott and White Health, Baylor University Medical Center, Dallas, Texas, USA.
Purpose Of Review: This study aims to examine the ethical and legal discourse surrounding normothermic regional perfusion (NRP) for donation after circulatory death (DCD).
Recent Findings: NRP is well established within Europe but faces challenges in the US and is not utilized in a variety of other countries. NRP compliance with the dead donor rule (DDR) and Uniform Declaration of Death Act (UDDA) is the most significant recently addressed US ethical and legal issue.
Epilepsy-heart syndrome: Concept, clinical context, and opportunity for integrated care.
Epilepsia
March 2025
Liverpool Centre for Cardiovascular Science at University of Liverpool, Liverpool John Moores University and Liverpool Heart and Chest Hospital, Liverpool, UK.
In this concept paper, we introduce epilepsy-heart syndrome as a shared burden of illness between epilepsy and cardiac disorders. This pragmatic definition is agnostic of which condition came first (the epilepsy or the cardiac disorder), recognising that these conditions can each serve as a risk factor for the other owing to a bidirectional relationship that exists between the brain and the heart. To provide clinical context, we include ictal asystole as an example phenotype of epilepsy-heart syndrome.
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