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Budget Impact Analysis of Integrative Medicine Practices for Pediatric Patients with Chronic Pain.
Clin J Pain
January 2025
Department of Anesthesiology Critical Care Medicine, The Saban Research Institute at Children's Hospital Los Angeles, The Biobehavioral Pain Lab.
Objectives: Chronic pain is a leading cause of morbidity in children and adolescents globally but can be managed with a combination of traditional Western medicine and integrative medicine (IM) practices. This combination has improved various critical health outcomes, such as quality-of-life, sleep, pain, anxiety, and healthcare utilization. These IM practices include acupuncture, yoga, biofeedback, massage, mindfulness, or any combination of these modalities.
View Article and Find Full Text PDFLongitudinal assessment of health-related quality of life in patients with adult congenital heart disease undergoing cardiac surgery.
JTCVS Open
December 2024
Division of Pediatric Cardiac Surgery, Heart, Vascular and Thoracic Institute, Cleveland Clinic Children's Hospital, Cleveland, Ohio.
Objective: The study objective was to assess longitudinal postoperative health-related quality of life among patients with adult congenital heart disease facilitated by a novel electronic medical record-based patient-reported outcomes follow-up platform.
Methods: From January 2022 to October 2023, 559 patients with adult congenital heart disease underwent cardiac surgery; 491 (88%) completed a 23-element health-related quality of life questionnaire covering 3 domains (physical, mental, and social) yielding 911 assessments. Automated questionnaires via electronic medical record were sent at 7 days preoperatively and postoperatively at 1, 3, 6, and 12 months.
Genomic characterization of Escherichia coli with a polyketide synthase (pks) island isolated from ulcerative colitis patients.
BMC Genomics
January 2025
Department of Population Medicine and Diagnostic Sciences, College of Veterinary Medicine, Cornell University, Ithaca, NY, USA.
The E. coli strains harboring the polyketide synthase (pks) island encode the genotoxin colibactin, a secondary metabolite reported to have severe implications for human health and for the progression of colorectal cancer. The present study involves whole-genome-wide comparison and phylogenetic analysis of pks harboring E.
View Article and Find Full Text PDFPangenome graphs and their applications in biodiversity genomics.
Nat Genet
January 2025
The Vertebrate Genome Laboratory, New York, NY, USA.
Complete datasets of genetic variants are key to biodiversity genomic studies. Long-read sequencing technologies allow the routine assembly of highly contiguous, haplotype-resolved reference genomes. However, even when complete, reference genomes from a single individual may bias downstream analyses and fail to adequately represent genetic diversity within a population or species.
View Article and Find Full Text PDFSuitability of Rosaceae fruit tree species for Panonychus citri (McGregor) (Acari: Tetranychidae).
Exp Appl Acarol
January 2025
College of Plant Protection, Shandong Agricultural University, Tai'an, 271018, China.
The citrus red mite (CRM), Panonychus citri (McGregor) (Acari: Tetranychidae), a worldwide pest chiefly infesting Citrus plants, has spread from Southern China to Northern China. Little information is known about the population performance of CRM on the plants except for citrus trees and pear trees. In order to evaluate the extent of damage might caused by CRM to the fruit trees cultivated in Northern China, the performance of CRM on four Rosaceae species, including three main fruit tree species (pear-Pyrus pyrifolia Nakai cv.
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