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Uncovering the Mechanism of Action of Antiprotozoal Agents: A Survey on Photoaffinity Labeling Strategy.
Pharmaceuticals (Basel)
December 2024
Dipartimento di Scienze della Vita, della Salute e delle Professioni Sanitarie, Università degli Studi "Link Campus University", Via del Casale di S. Pio V 44, I-00165 Rome, Italy.
, , and parasites are responsible for infectious diseases threatening millions of people worldwide. Despite more recent efforts devoted to the search for new antiprotozoal agents, efficacy, safety, and resistance issues still hinder the development of suited therapeutic options. The lack of robustly validated targets and the complexity of parasite's diseases have made phenotypic screening a preferential drug discovery strategy for the identification of new chemical entities.
View Article and Find Full Text PDFEfficacy and safety of intraoperative controlled hypotension. Comment on Br J Anaesth 2024; 133: 940-54.
Br J Anaesth
January 2025
AIZH Statistics, Melbourne, Australia. Electronic address:
[Application of artificial intelligence in parasitic diseases and parasitology].
Zhongguo Xue Xi Chong Bing Fang Zhi Za Zhi
December 2024
Department of Epidemiology, School of Public Health, Fudan University; Key Laboratory of Public Health Safety, Ministry of Education; Tropical Disease Research Center, Fudan University, Shanghai 200032, China.
The rapid development of artificial intelligence poses a huge impact on health and has become a core driving force for the new generation of the scientific and technological revolution in the field of healthcare. Recently, artificial intelligence has been gradually applied in the field of parasitic diseases and parasitology, including disease diagnosis, prognosis prediction, prediction of transmission risk, intelligent identification of vectors and intermediate hosts, and disease prevention and control, which facilitates the progress towards elimination of parasitic diseases. In addition, artificial intelligence provides highly efficient tools and approaches for healthcare workers and researchers.
View Article and Find Full Text PDFLetter to the Editor Regarding "Geographical Differences in the Safety and Efficacy of Tofacitinib Versus TNFi: A Post Hoc Analysis of ORAL Surveillance".
Rheumatol Ther
January 2025
Department of Gastroenterology, All India Institute of Medical Sciences, New Delhi, India.
Admitted when Breastfeeding: Impact and Experiences of Hospital Care.
Breastfeed Med
January 2025
Department of Mathematics, Universitat Politècnica de Catalunya, Barcelona, Spain.
This study analyzes the impact and experiences of hospitalization for any reason on breastfeeding women. Cross-sectional online survey (November 2019-March 2020). Adults admitted to a Spanish hospital for at least one night, when actively breastfeeding, were included.
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