AI Article Synopsis
- The transport of molecules and ions is influenced by the confinement effect of biological ion channels, which have very small pores (angstrom-sized).
- The study focuses on comparing the potassium channel's structure and ZIF-8’s intrinsic pores, highlighting their similarities.
- A glass/ZIF-8 hybrid membrane was created to study ion transport using electrochemical methods, revealing that ion transport behaves according to Arrhenius principles, where ionic charge and size are significant factors.
Article Abstract
The confinement effect of biological ion channels regulates the transport of molecules and ions due to angstrom-sized pores. The structure of the potassium channel has a selection region (3-4 Å), a cavity (10 Å), and a gated region, while ZIF-8 has intrinsic pores with a 3.4 Å aperture and an 11.6 Å cavity similar to those of the potassium channel. Inspired by this, we constructed the glass/ZIF-8 hybrid membrane through an electrochemical growth process to explore the kinetics of the ion transmembrane by - curves and electrochemical impedance spectroscopy. These complementary approaches yield highly correlated results that show that ion transportation of the ZIF-8 membrane follows Arrhenius behavior. The rates of ions are controlled by the transmembrane activation energy, in which the ionic charge and radius play an important role.
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| http://dx.doi.org/10.1021/acs.jpclett.1c01469 | DOI Listing |
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