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Global strategies for preventing type 2 diabetes: A public health perspective.
Indian J Med Res
November 2024
Department of Pediatrics, University of Alabama at Birmingham, Division of Pediatric Endocrinology and Diabetes, Alabama, 35233, United States.
Association between internet use and primary headache severity among Hungarian university students: a cross-sectional study.
Front Public Health
December 2024
Department of Ophtalmology, Medical School, University of Pécs, Pécs, Hungary.
Background: Recent studies suggest that increased digital technology usage could be a factor in the rising occurrence and severity of headache episodes. The purpose of this cross-sectional study was to determine whether the severity of primary headaches (migraine and tension-type headache) is associated with problematic internet use taking many covariates into account.
Methods: We conducted an online cross-sectional survey using a quantitative, descriptive questionnaire, targeting university students enrolled in correspondence courses, aged 18 to 65.
Metformin improves infection by strengthening macrophage antimicrobial functions.
Front Immunol
December 2024
Centre of Molecular Inflammation Research, Department of Molecular and Clinical Medicine, Faculty of Medicine and Health Sciences, Norwegian University of Science and Technology (NTNU), Trondheim, Norway.
Introduction: The incidence and prevalence of infections with non-tuberculous mycobacteria such as (Mav) are increasing. Prolonged drug regimens, inherent antibiotic resistance, and low cure rates underscore the need for improved treatment, which may be achieved by combining standard chemotherapy with drugs targeting the host immune system. Here, we examined if the diabetes type 2 drug metformin could improve Mav-infection.
View Article and Find Full Text PDFC3 deficiency promotes pulmonary inflammation in AT1R-induced mouse model for systemic sclerosis.
Front Immunol
December 2024
Priority Area Chronic Lung Diseases, Research Center Borstel - Leibniz Lung Center, Members of the German Center for Lung Research (DZL), Borstel, Germany.
Introduction: Autoantibody-mediated complement activation plays an essential role in a variety of autoimmune disorders. However, the role of complement in systemic sclerosis (SSc) remains largely unknown. In this study, we aimed to determine the role of complement C3 in the development of a recently described SSc mouse model based on autoimmunity to angiotensin II receptor type 1 (AT1R).
View Article and Find Full Text PDFAdvancements in lipid production research using the koji-mold and future outlook.
Front Fungal Biol
December 2024
Bioproduction Research Institute, National Institute of Advanced Industrial Science and Technology (AIST), Sapporo, Japan.
Research on enhancing the production of lipids, particularly polyunsaturated fatty acids that are considered important for health, has focused on improvement of metabolism as well as heterologous expression of biosynthetic genes in the oleaginous fungus . To date, the productivity and production yield of free fatty acids have been enhanced by 10-fold to 90-fold via improvements in metabolism and optimization of culture conditions. Moreover, the productivity of ester-type fatty acids present in triacylglycerols could be enhanced via metabolic improvement.
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