Ischemic cholangiopathy is a feared complication after liver transplantation. We present a 68-year-old man who is status postorthotopic liver transplant from a donation after cardiac death. His posttransplant course was complicated by the development of a biliary anastomotic stricture, ischemic cholangiopathy, biloma, recurrent cholangitis, and intrahepatic stones. Through the use of antegrade cholangioscopy with a single-operator cholangioscope (SpyGlass 2; Boston Scientific, Boston, MA) passed through a percutaneous sheath, we were able to visualize impacted stones within the left intrahepatic system and treat them using electrohydraulic lithotripsy for stone fragmentation and removal.
Download full-text PDF |
Source |
|---|---|
| http://www.ncbi.nlm.nih.gov/pmc/articles/PMC8177873 | PMC |
| http://dx.doi.org/10.14309/crj.0000000000000595 | DOI Listing |
Publication Analysis
Top Keywords
Similar Publications
Outcomes of DCD Liver Transplant Using Sequential Normothermic Regional Perfusion and Normothermic Machine Perfusion or NRP Alone Versus Static Cold Storage.
Transplantation
December 2024
Department of Transplant, Mayo Clinic Florida, Jacksonville, FL.
Background: The availability of in situ normothermic regional perfusion (NRP) or ex situ normothermic machine perfusion (NMP) has revolutionized donation after circulatory death (DCD) liver transplant (LT). While some have suggested that NRP and NMP may represent competing technologies for DCD LT, there are many scenarios where these technologies can function in a complementary manner.
Methods: Between January 2022 and March 2024, 83 DCD LTs were performed using NRP (62 NRP alone and 21 NRP + NMP) and were compared with 297 static cold storage (SCS) DCD LTs.
Preservation of coagulation function by normothermic machine perfusion in liver transplant as evidenced by thromboelastography parameters.
Liver Transpl
October 2024
Department of Anesthesiology and Perioperative Medicine, Mayo Clinic in Arizona, Phoenix, Arizona, USA.
The use of normothermic machine perfusion (NMP) over static cold storage in liver transplantation has been shown to reduce posttransplant risks of early allograft dysfunction, primary nonfunction, and ischemic cholangiopathy, and its increasing use has played a role in the expanded utilization of marginal livers. While studies have demonstrated improved clinical outcomes using NMP over static cold storage preservation, real-time intraoperative data reflecting the quality and viability of NMP livers is limited. This retrospective, single-center study compared NMP versus static cold storage livers in first-time recipients of liver transplants through the evaluation of synthetic coagulation function as measured by thromboelastography and conventional coagulation testing.
View Article and Find Full Text PDFImproving Diagnosis of Acute Cholecystitis with US: New Paradigms.
Radiographics
December 2024
From the Departments of Radiology (R.P., J.R.T., L.S., A.K.) and Pathology (D.B.B.), Stanford University, 300 Pasteur Dr, Palo Alto, CA 94304.
Acute cholecystitis is an inflammatory condition of the gallbladder typically incited by mechanical obstruction. Accurate diagnosis of this common clinical condition is challenging due to variable imaging appearances as well as overlapping clinical manifestations with biliary colic, acute hepatitis, pancreatitis, and cholangiopathies. In acute cholecystitis, increased dilatation and high intraluminal pressures lead to gallbladder inflammation and may progress to gangrenous changes, focal wall necrosis, and subsequent perforation.
View Article and Find Full Text PDFImaging of Ischemic Cholangiopathy Following Donation after Circulatory Death Liver Transplant.
Radiographics
November 2024
From the Departments of Radiology (M.Z., M.S., M.Y.) and Gastroenterology and Hepatology (C.J., R.P., B.A.), Mayo Clinic Arizona, 13400 E Shea Blvd, Scottsdale, AZ 85259; Department of Radiology, Mayo Clinic Rochester, Rochester, Minn (S.K.V.); Department of Anatomical Pathology, Singapore General Hospital, Singapore (J.T.L.); and Mallinckrodt Institute of Radiology, Washington University School of Medicine, St. Louis, Mo (D.R.L., D.H.B.).
Article Synopsis
Early outcome of machine perfusion vs static cold storage of liver graft: A systemic review and meta-analysis of randomized controlled trials.
Hepatol Forum
March 2024
Department of Surgery, Aminu Kano Teaching Hospital, Kano, Nigeria.
The use of marginal grafts is very challenging and is associated with post-reperfusion syndrome and early allograft dysfunction. The outcomes of machine perfusion for the preservation of marginal grafts have been compared with that of static cold storage, with studies reporting a reduced risk of ischemic cholangiopathy and graft loss. We performed this systematic review and meta-analysis of randomized controlled trials (RCTs) comparing outcomes of machine perfusion of liver grafts to static cold storage (SCS) of liver grafts during liver transplantation.
View Article and Find Full Text PDFWant AI Summaries of new PubMed Abstracts delivered to your In-box?
Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!