Neurinomas of the hypoglossal nerve are rarely reported. In most cases these tumors are intracranial or sited at the skull base. Only a few solitary neurinomas of the twelfth cranial nerve have been reported. In most of these cases the tumors arose from the descending part of the nerve in the parapharyngeal space. We report the first neurinoma recorded arising from the submandibular course of the hypoglossal nerve.

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