[Microdosing LSD: practices and risks].

The practice of microdosing, which consists of ingesting a hallucinogen at 5-10% of a dose that would induce a psychedelic effect, has recently been the subject of growing interest by the media. The craze for microdosing has been relayed by the supposed effects of increased performance and creativity reported by professionals, especially in Silicon Valley. Despite this strong public interest, the evidence supporting this practice remains preliminary. Available studies are mostly based on single doses, leaving open the question of a possible stronger effect with regular doses. LSD's main effect is on the serotonin system, in particular on 5-HT2A receptors, a receptor involved in neurobiological processes underlying learning.