Much is unknown about assisted hydration at the end of life: why rates of usage vary so highly between institutions, cultures and countries, what beneficial or burdensome effects this treatment has, whether there is a place for subcutaneous hydration in the home setting, and how best to communicate about this difficult topic with dying people and their families. In light of a recently published systematic review concerning the impact of assisted hydration at the end of life, this article explores these questions and related issues, concluding that individualisation and shared decision-making are essential aspects of high-quality end-of-life care.
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http://dx.doi.org/10.12968/bjcn.2021.26.6.284 | DOI Listing |
J Manag Care Spec Pharm
January 2025
Department of Pharmacy, Cleveland Clinic, OH.
Background: Heart failure is a prevalent disease state associated with limitations in function, hospitalization, and death. The 2022 American Heart Association/American College of Cardiology/Heart Failure Society of America guidelines recommend medications including sacubitril/valsartan to decrease morbidity and mortality in patients with heart failure. However, if patients are nonadherent to treatment or experience barriers to care, they will forgo these benefits.
View Article and Find Full Text PDFNurs Rep
December 2024
Department of Philosophy, Idaho State University, Pocatello, ID 83209, USA.
Background/objectives: Caring for patients at the end of life can involve issues that are ethically and legally fraught: withholding or withdrawing artificial nutrition and hydration, pain control that could hasten death, aggressive treatment that is continued when it seems only to be prolonging suffering, patients who request medical assistance in dying, and so forth. Clinicians may find that their deeply held ethical principles conflict with law, institutional policy, or patients' choices. In these situations, they may consider either refusing to participate in procedures that they find morally abhorrent (conscientious refusal) or providing care that they believe to be ethically obligatory despite being contrary to law or policy (conscientious commitment).
View Article and Find Full Text PDFSemin Oncol Nurs
December 2024
Department of Psychiatry & Behavioral Sciences, Memorial Sloan Kettering Cancer Center, New York, New York.
Objectives: This paper addresses nutritional challenges in advanced cancer and at the end of life and implications for oncology nursing practice.
Methods: Recent literature and position statements regarding nutritional support in advanced disease and at the end of life were reviewed and case studies were developed to illustrate the nutritional issues facing patients and family members.
Results: The literature and case examples illustrate the many issues confronting patients, families, and clinicians related to nutritional support including balancing the goals of comfort versus prolonged survival.
Ageing Res Rev
December 2024
Department of Orthopedics, The First Affiliated Hospital of Zhengzhou University, Zhengzhou 450052, China. Electronic address:
The circadian clock orchestrates a broad spectrum of physiological processes, crucially modulating human biology across an approximate 24-hour cycle. The circadian disturbances precipitated by modern lifestyle contribute to the occurrence of low back pain (LBP), mainly ascribed to intervertebral disc degeneration (IVDD). The intervertebral disc (IVD) exhibits rhythmic physiological behaviors, with fluctuations in osmotic pressure and hydration levels that synchronized with the diurnal cycle of activity and rest.
View Article and Find Full Text PDFMaterials (Basel)
December 2024
School of Transportation and Civil Engineering, Nantong University, Nantong 226019, China.
Understanding the enhancing mechanisms of graphene oxide (GO) on the pore structure characteristics in the interfacial transition zone (ITZ) plays a crucial role in cemented waste rock backfill (CWRB) nanoreinforcement. In the present work, an innovative method based on metal intrusion techniques, backscattered electron (BSE) images, and deep learning is proposed to analyze the micro/nanoscale characteristics of microstructures in the GO-enhanced ITZ. The results showed that the addition of GO reduced the interpore connectivity and the porosity at different pore throats by 53.
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