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Interferon activation in bone marrow long-lived plasma cells in systemic lupus erythematosus.
Front Immunol
January 2025
Division of Allergy, Immunology and Rheumatology, University of Rochester Medical Center, Rochester, NY, United States.
While durable antibody responses from long-lived plasma cell (LLPC) populations are important for protection against pathogens, LLPC may be harmful if they produce antibodies against self-proteins or self-nuclear antigens as occurs in autoimmune diseases such as systemic lupus erythematosus (SLE). Thus, the elimination of autoreactive LLPC may improve the treatment of antibody-driven autoimmune diseases. However, LLPC remain a challenging therapeutic target.
View Article and Find Full Text PDFDribble deficit as an effective measure of dribbling ability independent of sprinting performance in professional female handball players.
Front Physiol
January 2025
Faculty of Sport and Physical Education, University of Niš, Niš, Serbia.
Purpose: The purpose of this study was to determine the relationship between linear and change-of-direction sprinting performance with dribbling performance and Dribble Deficit in professional female handball players.
Methods: Eleven professional female handball players (mean age: 21.12 ± 4.
Shaping the Future of "Cardio-Kidney-Metabolic" Health: Insights From The Texas Heart Institute's 2024 Cardiometabolic Syndrome Conference.
Tex Heart Inst J
January 2025
Department of Cardiology, The Texas Heart Institute at Baylor College of Medicine, Houston, Texas.
At the Texas Heart Institute's 2024 Cardiometabolic Syndrome Conference, held on August 23, 2024, experts from diverse academic fields spoke about novel initiatives for addressing the worsening projections for cardiometabolic syndrome. Four major areas in which innovation is ongoing were highlighted: technology, policy, population health, and lifestyle and behavioral modification. This article presents a brief contextualization, summary, and analysis of the novel initiatives being implemented in each of these 4 areas to address cardiometabolic syndrome.
View Article and Find Full Text PDFInfluence of Smartphone Usage on development of Sexuality among Late Adolescent Boys in Health Sciences Colleges of South India.
F1000Res
January 2025
Department of Community Medicine, Kasturba Medical College, Mangalore, Manipal Academy of Higher Education,, Karnataka, Manipal, 576104, India.
Background: Better affordability of data plans and an increase in "budget" smartphones have resulted in an exponential rise in internet and smartphone users. The ease of access to sexually explicit material (SEM) coupled with adolescents' impulsivity makes them prone to excessive SEM exposure and may affect the development of sexuality via the perceived realism of such content. This study was done to study the influence between problematic smartphone usage (PSU) and sexuality development among late adolescent boys.
View Article and Find Full Text PDFReal-Time Monitoring of Electrode Surface Changes in Fast-Scan Cyclic Voltammetry Using Fourier Transform Electrochemical Impedance Spectroscopy.
ACS Omega
January 2025
Department of Biomedical Engineering, Hanyang University, Seoul 04763, Republic of Korea.
Fast-scan cyclic voltammetry (FSCV) is a widely used electrochemical technique to measure the phasic response of neurotransmitters in the brain. It has the advantage of reducing tissue damage to the brain due to the use of carbon fiber microelectrodes as well as having a high temporal resolution (10 Hz) sufficient to monitor neurotransmitter release in vivo. During the FSCV experiment, the surface of the carbon fiber microelectrode is inevitably changed by the fouling effect.
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