Otitis is a serious and noteworthy disease. Only timely and adequate treatment guarantees to cure it and prevent complications. The present study involved 250 patients, raining in age from 2 to 64 years. Patients' data were anonymous and cannot be identified. 125 patients were diagnosed with middle purulent otitis, 20 with middle secretory otitis, 78 with external diffuse otitis, and 27 with external otitis media.The aim of the research was to determine the efficacyof antibiotic-contained ear drops in the treatment of acute otitis media, in combination with mono- or systemic antibiotics. The data were analyzed utilizing the descriptive statistics. The frequency distribution of variables was also determined and the results were presented in appropriate numeric values and percentages.

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